Varaico: Literature-Extracted Genetic Variants

Gene:ACE2
Variant:p.R716C
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ACE2

NM_001371415.1:p.R716C

Associated Papers

Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.

Talebi T et al.

Genetics Research, 2023

Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.

Rodriguez JA et al.

Chemico-biological Interactions, 2022

36336003 (PubMed )
Supplement: mmc1.pdf

Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS-CoV-2 from 946 whole-exome sequencing data in the Turkish population.

Duman N et al.

Journal of Medical Virology, 2022

Human genetic basis of coronavirus disease 2019.

Deng H et al.

Signal Transduction and Targeted Therapy, 2021

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.

Suryamohan K et al.

Communications Biology, 2021

33846513 (PubMed )
Supplement: 42003_2021_2030_MOESM1_ESM.pdf

In Silico Analysis of High-Risk Missense Variants in Human ACE2 Gene and Susceptibility to SARS-CoV-2 Infection.

Saih A et al.

Biomed Research International, 2021

Pan-Cancer Analysis of Genomic and Prognostic Characteristics Associated With Coronavirus Disease 2019 Regulators.

Zhang J et al.

Frontiers in Medicine, 2021

34458283 (PubMed )
Supplement: Table_1.XLS › ACE2

Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.

Sorokina M et al.

Scientific Data, 2020

Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).

Guo X et al.

Journal of Translational Medicine, 2020

32831104 (PubMed )
Supplement: 12967_2020_2486_MOESM1_ESM.xls › gnomAD_v2.1.1_ENSG00000130234_2

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis.

Hou Y et al.

Bmc Medicine, 2020

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