Associated Papers
Comparative analysis of ACE2 mutations and their impact on SARS-CoV-2 susceptibility within diverse ethnic groups.
Shafique R et al.
Journal of Biomolecular Structure & Dynamics, 2026
Association of specific ACE2 and TMPRSS2 variants with circulatory cytokines of COVID-19 Emirati patients.
Elemam NM et al.
Frontiers in Immunology, 2024
Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.
Talebi T et al.
Genetics Research, 2023
Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.
Rodriguez JA et al.
Chemico-biological Interactions, 2022
Characterization of ACE2 naturally occurring missense variants: impact on subcellular localization and trafficking.
Badawi S et al.
Human Genomics, 2022
Human ACE2 Polymorphisms from Different Human Populations Modulate SARS-CoV-2 Infection.
Hu P et al.
Viruses, 2022
Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants.
Zhang Y et al.
Cell Reports, 2022
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.
MacGowan SA et al.
Plos Computational Biology, 2022
An overview of human proteins and genes involved in SARS-CoV-2 infection.
Jahanafrooz Z et al.
Gene, 2022
Longitudinal analysis of SARS-CoV-2 spike and RNA-dependent RNA polymerase protein sequences reveals the emergence and geographic distribution of diverse mutations.
Showers WM et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2022
Human genetic basis of coronavirus disease 2019.
Deng H et al.
Signal Transduction and Targeted Therapy, 2021
SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution.
Zahradník J et al.
Nature Microbiology, 2021
Vaccine-escape and fast-growing mutations in the United Kingdom, the United States, Singapore, Spain, India, and other COVID-19-devastated countries.
Wang R et al.
Genomics, 2021
SARS-CoV-2 receptor-binding mutations and antibody contact sites.
Mejdani M et al.
Antibody Therapeutics, 2021
Enhanced binding of the N501Y-mutated SARS-CoV-2 spike protein to the human ACE2 receptor: insights from molecular dynamics simulations.
Luan B et al.
Febs Letters, 2021
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.
Suryamohan K et al.
Communications Biology, 2021
Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro.
Hashizume M et al.
Viruses, 2021
A Computational Approach to Evaluate the Combined Effect of SARS-CoV-2 RBD Mutations and ACE2 Receptor Genetic Variants on Infectivity: The COVID-19 Host-Pathogen Nexus.
Ashoor D et al.
Frontiers in Cellular and Infection Microbiology, 2021
ACE2 coding variants in different populations and their potential impact on SARS-CoV-2 binding affinity.
Ali F et al.
Biochemistry and Biophysics Reports, 2020
Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2.
Mohammad A et al.
Life Sciences, 2020
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M et al.
Scientific Data, 2020
Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).
Guo X et al.
Journal of Translational Medicine, 2020
Genetic variability of human angiotensin-converting enzyme 2 (hACE2) among various ethnic populations.
Li Q et al.
Molecular Genetics & Genomic Medicine, 2020