Varaico: Literature-Extracted Genetic Variants

Gene:ACE2
Variant:p.K458R
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ACE2

NM_001371415.1:p.K458R

Associated Papers

Rational design of a covalent ACE2 decoy receptor that broadly neutralizes SARS-CoV-2 variants.

Hino N et al.

Protein Science : a Publication of the Protein Society, 2025

Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity.

Okal EF et al.

Journal of Biological Engineering, 2025

39901286 (PubMed )
Supplement: 13036_2025_482_MOESM3_ESM.xlsx › table_for_paper

Inhibitor screening using microarray identifies the high capacity of neutralizing antibodies to Spike variants in SARS-CoV-2 infection and vaccination.

Zhang X et al.

Theranostics, 2022

35401825 (PubMed )
Supplement: thnov12p2519s1.pdf

Vaccine-escape and fast-growing mutations in the United Kingdom, the United States, Singapore, Spain, India, and other COVID-19-devastated countries.

Wang R et al.

Genomics, 2021

34004284 (PubMed )
Supplement: mmc2.pdf

Mutations in the SARS-CoV-2 spike protein modulate the virus affinity to the human ACE2 receptor, an in silico analysis.

Ortega JT et al.

Excli Journal, 2021

A Computational Approach to Evaluate the Combined Effect of SARS-CoV-2 RBD Mutations and ACE2 Receptor Genetic Variants on Infectivity: The COVID-19 Host-Pathogen Nexus.

Ashoor D et al.

Frontiers in Cellular and Infection Microbiology, 2021

34434902 (PubMed )
Supplement: DataSheet_4.xlsx › Sheet1

The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity.

Li Q et al.

Cell, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."