Associated Papers
Host genetic variation governs PCV2 susceptibility through CXCL13 and ELK1-mediated immune regulation.
Liu G et al.
International Journal of Biological Macromolecules, 2025
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics.
Waman VP et al.
Scientific Reports, 2024
Polymorphisms in the human angiotensin converting enzyme gene (ACE) linked to susceptibility of COVID-19 and malaria infections in the Ghanaian population.
Duah-Quashie NO et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2024
Intronic Variants of the Angiotensin-Converting Enzyme 2 Gene Modulate Plasma ACE2 Levels and Possibly Confer Protection against Severe COVID-19.
Ahmed R et al.
Biomed Research International, 2023
Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.
Talebi T et al.
Genetics Research, 2023
Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.
Rodriguez JA et al.
Chemico-biological Interactions, 2022
Structural Profiles of SARS-CoV-2 Variants in India.
Chakraborti S et al.
Current Microbiology, 2022
Receptor binding domain of SARS-CoV-2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2.
Patil S et al.
Journal of Infection and Public Health, 2022
Association of polymorphisms in tumor necrosis factors with SARS-CoV-2 infection and mortality rate: A case-control study and in silico analyses.
Heidari Nia M et al.
Journal of Medical Virology, 2022
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.
MacGowan SA et al.
Plos Computational Biology, 2022
Identification of destabilizing SNPs in SARS-CoV2-ACE2 protein and spike glycoprotein: implications for virus entry mechanisms.
Khalid Z et al.
Journal of Biomolecular Structure & Dynamics, 2022
An overview of human proteins and genes involved in SARS-CoV-2 infection.
Jahanafrooz Z et al.
Gene, 2022
Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.
Ren W et al.
Journal of Virology, 2022
SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds.
Vadgama N et al.
Frontiers in Genetics, 2022
The role of angiotensin-converting enzyme 2 (ACE2) genetic variations in COVID-19 infection: a literature review.
Fawzy MS et al.
The Egyptian Journal of Medical Human Genetics, 2022
Human genetic basis of coronavirus disease 2019.
Deng H et al.
Signal Transduction and Targeted Therapy, 2021
Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2.
Bhattacharjee MJ et al.
Molecular Biology and Evolution, 2021
Genetic variations in the human severe acute respiratory syndrome coronavirus receptor ACE2 and serine protease TMPRSS2.
Fujikura K et al.
Journal of Clinical Pathology, 2021
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.
Suryamohan K et al.
Communications Biology, 2021
In Silico Analysis of High-Risk Missense Variants in Human ACE2 Gene and Susceptibility to SARS-CoV-2 Infection.
Saih A et al.
Biomed Research International, 2021
The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy.
Chen F et al.
Frontiers in Cellular and Infection Microbiology, 2021
Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).
Guo X et al.
Journal of Translational Medicine, 2020
SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.
Gupta R et al.
The Journal of Biological Chemistry, 2020
Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of Outcome.
Shikov AE et al.
Frontiers in Genetics, 2020