Associated Papers
Comparative analysis of ACE2 mutations and their impact on SARS-CoV-2 susceptibility within diverse ethnic groups.
Shafique R et al.
Journal of Biomolecular Structure & Dynamics, 2026
Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity.
Okal EF et al.
Journal of Biological Engineering, 2025
39901286 (PubMed )
Supplement: 13036_2025_482_MOESM3_ESM.xlsx › table_for_paper
Human variation in the protein receptor ACE2 affects its binding affinity to SARS-CoV-2 in a variant-dependent manner.
Santos TM et al.
Journal of Biomolecular Structure & Dynamics, 2023
Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.
Rodriguez JA et al.
Chemico-biological Interactions, 2022
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.
MacGowan SA et al.
Plos Computational Biology, 2022
35235558 (PubMed )
Supplement: pcbi.1009922.s001.xlsx › Sheet1
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.
Suryamohan K et al.
Communications Biology, 2021
33846513 (PubMed )
Supplement: 42003_2021_2030_MOESM1_ESM.pdf
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M et al.
Scientific Data, 2020
Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).
Guo X et al.
Journal of Translational Medicine, 2020
32831104 (PubMed )
Supplement: 12967_2020_2486_MOESM1_ESM.xls › gnomAD_v2.1.1_ENSG00000130234_2
Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of Outcome.
Shikov AE et al.
Frontiers in Genetics, 2020
33133145 (PubMed )
Supplement: Data_Sheet_2.xlsx › Table_S7
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