Associated Papers
Molecular insights and optimization strategies for the competitive binding of engineered ACE2 proteins: a multiple replica molecular dynamics study.
Sun J et al.
Physical Chemistry Chemical Physics : Pccp, 2023
Optimizing variant-specific therapeutic SARS-CoV-2 decoys using deep-learning-guided molecular dynamics simulations.
Köchl K et al.
Scientific Reports, 2023
36641503 (PubMed )
Supplement: 41598_2023_27636_MOESM3_ESM.pdf
Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants.
Bodie NM et al.
Antibody Therapeutics, 2023
Understanding the Driving Forces That Trigger Mutations in SARS-CoV-2: Mutational Energetics and the Role of Arginine Blockers in COVID-19 Therapy.
Ridgway H et al.
Viruses, 2022
Engineered small extracellular vesicles displaying ACE2 variants on the surface protect against SARS-CoV-2 infection.
Kim HK et al.
Journal of Extracellular Vesicles, 2022
S19W, T27W, and N330Y mutations in ACE2 enhance SARS-CoV-2 S-RBD binding toward both wild-type and antibody-resistant viruses and its molecular basis.
Ye F et al.
Signal Transduction and Targeted Therapy, 2021
Fast Prediction of Binding Affinities of the SARS-CoV-2 Spike Protein Mutant N501Y (UK Variant) with ACE2 and Miniprotein Drug Candidates.
Williams AH et al.
The Journal of Physical Chemistry. B, 2021
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