Associated Papers
Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity.
Okal EF et al.
Journal of Biological Engineering, 2025
Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.
Talebi T et al.
Genetics Research, 2023
Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.
Rodriguez JA et al.
Chemico-biological Interactions, 2022
Structural genetics of circulating variants affecting the SARS-CoV-2 spike/human ACE2 complex.
Ortuso F et al.
Journal of Biomolecular Structure & Dynamics, 2022
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.
MacGowan SA et al.
Plos Computational Biology, 2022
An overview of human proteins and genes involved in SARS-CoV-2 infection.
Jahanafrooz Z et al.
Gene, 2022
Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.
Ren W et al.
Journal of Virology, 2022
Structural Modeling of the SARS-CoV-2 Spike/Human ACE2 Complex Interface can Identify High-Affinity Variants Associated with Increased Transmissibility.
Gan HH et al.
Journal of Molecular Biology, 2021
Genetic variations in the human severe acute respiratory syndrome coronavirus receptor ACE2 and serine protease TMPRSS2.
Fujikura K et al.
Journal of Clinical Pathology, 2021
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.
Suryamohan K et al.
Communications Biology, 2021
Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19.
Choudhary S et al.
Annals of Laboratory Medicine, 2021
The impact of certain genetic variants (single nucleotide polymorphisms) on incidence and severity of COVID-19.
Abobaker A et al.
The Journal of Gene Medicine, 2021
COVID-19: The Effect of Host Genetic Variations on Host-Virus Interactions.
Chakravarty S
Journal of Proteome Research, 2021
The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy.
Chen F et al.
Frontiers in Cellular and Infection Microbiology, 2021
ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population.
Benetti E et al.
European Journal of Human Genetics : Ejhg, 2020
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M et al.
Scientific Data, 2020
Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).
Guo X et al.
Journal of Translational Medicine, 2020
SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.
Gupta R et al.
The Journal of Biological Chemistry, 2020