Varaico: Literature-Extracted Genetic Variants

Gene:ACE2
Variant:p.D206G
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ACE2

NM_001371415.1:p.D206G

Associated Papers

Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity.

Okal EF et al.

Journal of Biological Engineering, 2025

39901286 (PubMed )
Supplement: 13036_2025_482_MOESM3_ESM.xlsx › table_for_paper

Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.

Talebi T et al.

Genetics Research, 2023

Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.

MacGowan SA et al.

Plos Computational Biology, 2022

35235558 (PubMed )
Supplement: pcbi.1009922.s001.xlsx › Sheet1

An overview of human proteins and genes involved in SARS-CoV-2 infection.

Jahanafrooz Z et al.

Gene, 2022

SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds.

Vadgama N et al.

Frontiers in Genetics, 2022

Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis.

Dieter C et al.

Plos One, 2022

35793369 (PubMed )
Supplement: pone.0270627.s002.xlsx › Planilha1

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.

Suryamohan K et al.

Communications Biology, 2021

33846513 (PubMed )
Supplement: 42003_2021_2030_MOESM1_ESM.pdf

The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy.

Chen F et al.

Frontiers in Cellular and Infection Microbiology, 2021

ACE2 coding variants in different populations and their potential impact on SARS-CoV-2 binding affinity.

Ali F et al.

Biochemistry and Biophysics Reports, 2020

ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population.

Benetti E et al.

European Journal of Human Genetics : Ejhg, 2020

Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.

Sorokina M et al.

Scientific Data, 2020

Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).

Guo X et al.

Journal of Translational Medicine, 2020

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.

Hu H et al.

Molecular Psychiatry, 2016

25644381 (PubMed )
Supplement: mp2014193x1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."