Varaico: Literature-Extracted Genetic Variants

Gene:ACE2
Variant:p.M82I
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ACE2

NM_001371415.1:p.M82I

Associated Papers

Impact of African-Specific ACE2 Polymorphisms on Omicron BA.4/5 RBD Binding and Allosteric Communication Within the ACE2-RBD Protein Complex.

Barozi V et al.

International Journal of Molecular Sciences, 2025

Genetic Variants within SARS-CoV-2 Human Receptor Genes May Contribute to Variable Disease Outcomes in Different Ethnicities.

Adimulam T et al.

International Journal of Molecular Sciences, 2023

Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.

Talebi T et al.

Genetics Research, 2023

Structural Profiles of SARS-CoV-2 Variants in India.

Chakraborti S et al.

Current Microbiology, 2022

Structural genetics of circulating variants affecting the SARS-CoV-2 spike/human ACE2 complex.

Ortuso F et al.

Journal of Biomolecular Structure & Dynamics, 2022

Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.

MacGowan SA et al.

Plos Computational Biology, 2022

An overview of human proteins and genes involved in SARS-CoV-2 infection.

Jahanafrooz Z et al.

Gene, 2022

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.

Ren W et al.

Journal of Virology, 2022

Genetic variations affecting ACE2 protein stability in minority populations.

Mahase V et al.

Frontiers in Medicine, 2022

Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2.

Bhattacharjee MJ et al.

Molecular Biology and Evolution, 2021

Genetic variations in the human severe acute respiratory syndrome coronavirus receptor ACE2 and serine protease TMPRSS2.

Fujikura K et al.

Journal of Clinical Pathology, 2021

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.

Suryamohan K et al.

Communications Biology, 2021

33846513 (PubMed )
Supplement: 42003_2021_2030_MOESM1_ESM.pdf

Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein.

Calcagnile M et al.

Biochimie, 2021

The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy.

Chen F et al.

Frontiers in Cellular and Infection Microbiology, 2021

Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.

Sorokina M et al.

Scientific Data, 2020

Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).

Guo X et al.

Journal of Translational Medicine, 2020

32831104 (PubMed )
Supplement: 12967_2020_2486_MOESM1_ESM.xls › gnomAD_v2.1.1_ENSG00000130234_2

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target.

Dufva O et al.

Nature Communications, 2018

29674644 (PubMed )
Supplement: 41467_2018_3987_MOESM6_ESM.xlsx › NKTCL_L10
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