Associated Papers
Impact of African-Specific ACE2 Polymorphisms on Omicron BA.4/5 RBD Binding and Allosteric Communication Within the ACE2-RBD Protein Complex.
Barozi V et al.
International Journal of Molecular Sciences, 2025
Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.
Talebi T et al.
Genetics Research, 2023
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.
MacGowan SA et al.
Plos Computational Biology, 2022
35235558 (PubMed )
Supplement: pcbi.1009922.s001.xlsx › Sheet1
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain.
Nabel KG et al.
Science (new York, N.y.), 2022
34855508 (PubMed )
Supplement: science.abl6251_sm.pdf
Structural Modeling of the SARS-CoV-2 Spike/Human ACE2 Complex Interface can Identify High-Affinity Variants Associated with Increased Transmissibility.
Gan HH et al.
Journal of Molecular Biology, 2021
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.
Suryamohan K et al.
Communications Biology, 2021
33846513 (PubMed )
Supplement: 42003_2021_2030_MOESM1_ESM.pdf
Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein.
Calcagnile M et al.
Biochimie, 2021
ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population.
Benetti E et al.
European Journal of Human Genetics : Ejhg, 2020
Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).
Guo X et al.
Journal of Translational Medicine, 2020
32831104 (PubMed )
Supplement: 12967_2020_2486_MOESM1_ESM.xls › gnomAD_v2.1.1_ENSG00000130234_2
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