Varaico: Literature-Extracted Genetic Variants

Gene:ACE2
Variant:p.E35K
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ACE2

NM_001371415.1:p.E35K

Associated Papers

Impact of African-Specific ACE2 Polymorphisms on Omicron BA.4/5 RBD Binding and Allosteric Communication Within the ACE2-RBD Protein Complex.

Barozi V et al.

International Journal of Molecular Sciences, 2025

Polymorphisms in the human angiotensin converting enzyme gene (ACE) linked to susceptibility of COVID-19 and malaria infections in the Ghanaian population.

Duah-Quashie NO et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2024

Molecular insights and optimization strategies for the competitive binding of engineered ACE2 proteins: a multiple replica molecular dynamics study.

Sun J et al.

Physical Chemistry Chemical Physics : Pccp, 2023

Antibody Fc-binding profiles and ACE2 affinity to SARS-CoV-2 RBD variants.

Haycroft ER et al.

Medical Microbiology and Immunology, 2023

Whole exome sequencing of 28 families of Danish descent reveals novel candidate genes and pathways in developmental dysplasia of the hip.

Dembic M et al.

Molecular Genetics and Genomics : Mgg, 2023

36454308 (PubMed )
Supplement: 438_2022_1980_MOESM4_ESM.xlsx › List_of_genes

Intronic Variants of the Angiotensin-Converting Enzyme 2 Gene Modulate Plasma ACE2 Levels and Possibly Confer Protection against Severe COVID-19.

Ahmed R et al.

Biomed Research International, 2023

Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.

Talebi T et al.

Genetics Research, 2023

Structural Profiles of SARS-CoV-2 Variants in India.

Chakraborti S et al.

Current Microbiology, 2022

Human ACE2 Polymorphisms from Different Human Populations Modulate SARS-CoV-2 Infection.

Hu P et al.

Viruses, 2022

An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo.

Ikemura N et al.

Science Translational Medicine, 2022

Association of polymorphisms in tumor necrosis factors with SARS-CoV-2 infection and mortality rate: A case-control study and in silico analyses.

Heidari Nia M et al.

Journal of Medical Virology, 2022

Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.

MacGowan SA et al.

Plos Computational Biology, 2022

An overview of human proteins and genes involved in SARS-CoV-2 infection.

Jahanafrooz Z et al.

Gene, 2022

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.

Ren W et al.

Journal of Virology, 2022

SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds.

Vadgama N et al.

Frontiers in Genetics, 2022

The role of angiotensin-converting enzyme 2 (ACE2) genetic variations in COVID-19 infection: a literature review.

Fawzy MS et al.

The Egyptian Journal of Medical Human Genetics, 2022

Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2.

Bhattacharjee MJ et al.

Molecular Biology and Evolution, 2021

Genetic variations in the human severe acute respiratory syndrome coronavirus receptor ACE2 and serine protease TMPRSS2.

Fujikura K et al.

Journal of Clinical Pathology, 2021

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.

Suryamohan K et al.

Communications Biology, 2021

ACE2 and FURIN variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19.

Al-Mulla F et al.

Heliyon, 2021

COVID-19: The Effect of Host Genetic Variations on Host-Virus Interactions.

Chakravarty S

Journal of Proteome Research, 2021

Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein.

Calcagnile M et al.

Biochimie, 2021

In Silico Analysis of High-Risk Missense Variants in Human ACE2 Gene and Susceptibility to SARS-CoV-2 Infection.

Saih A et al.

Biomed Research International, 2021

A Computational Approach to Evaluate the Combined Effect of SARS-CoV-2 RBD Mutations and ACE2 Receptor Genetic Variants on Infectivity: The COVID-19 Host-Pathogen Nexus.

Ashoor D et al.

Frontiers in Cellular and Infection Microbiology, 2021

Pan-Cancer Analysis of Genomic and Prognostic Characteristics Associated With Coronavirus Disease 2019 Regulators.

Zhang J et al.

Frontiers in Medicine, 2021

34458283 (PubMed )
Supplement: Table_1.XLS › ACE2

The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy.

Chen F et al.

Frontiers in Cellular and Infection Microbiology, 2021

Do genetic polymorphisms in angiotensin converting enzyme 2 (ACE2) gene play a role in coronavirus disease 2019 (COVID-19)?

Lippi G et al.

Clinical Chemistry and Laboratory Medicine, 2020

Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2).

Guo X et al.

Journal of Translational Medicine, 2020

32831104 (PubMed )
Supplement: 12967_2020_2486_MOESM1_ESM.xls › gnomAD_v2.1.1_ENSG00000130234_2

SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.

Gupta R et al.

The Journal of Biological Chemistry, 2020

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