Associated Papers
Comparative analysis of ACE2 mutations and their impact on SARS-CoV-2 susceptibility within diverse ethnic groups.
Shafique R et al.
Journal of Biomolecular Structure & Dynamics, 2026
Impact of African-Specific ACE2 Polymorphisms on Omicron BA.4/5 RBD Binding and Allosteric Communication Within the ACE2-RBD Protein Complex.
Barozi V et al.
International Journal of Molecular Sciences, 2025
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics.
Waman VP et al.
Scientific Reports, 2024
Polymorphisms in the human angiotensin converting enzyme gene (ACE) linked to susceptibility of COVID-19 and malaria infections in the Ghanaian population.
Duah-Quashie NO et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2024
Association of specific ACE2 and TMPRSS2 variants with circulatory cytokines of COVID-19 Emirati patients.
Elemam NM et al.
Frontiers in Immunology, 2024
Impact of ACE2 gene variations on COVID-19 pathogenicity in Pakistani patients.
Waryah YM et al.
Saudi Journal of Biological Sciences, 2023
Antibody Fc-binding profiles and ACE2 affinity to SARS-CoV-2 RBD variants.
Haycroft ER et al.
Medical Microbiology and Immunology, 2023
Genetic analysis of ACE2 peptidase domain in SARS-CoV-2-positive and SARS-CoV-2-negative individuals from Pakistan.
Muhammad N et al.
Molecular Biology Reports, 2023
Human variation in the protein receptor ACE2 affects its binding affinity to SARS-CoV-2 in a variant-dependent manner.
Santos TM et al.
Journal of Biomolecular Structure & Dynamics, 2023
Whole exome sequencing of 28 families of Danish descent reveals novel candidate genes and pathways in developmental dysplasia of the hip.
Dembic M et al.
Molecular Genetics and Genomics : Mgg, 2023
Human Genome Polymorphisms and Computational Intelligence Approach Revealed a Complex Genomic Signature for COVID-19 Severity in Brazilian Patients.
Pastor AF et al.
Viruses, 2023
Intronic Variants of the Angiotensin-Converting Enzyme 2 Gene Modulate Plasma ACE2 Levels and Possibly Confer Protection against Severe COVID-19.
Ahmed R et al.
Biomed Research International, 2023
Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19.
Talebi T et al.
Genetics Research, 2023
Computational modeling of the effect of five mutations on the structure of the ACE2 receptor and their correlation with infectivity and virulence of some emerged variants of SARS-CoV-2 suggests mechanisms of binding affinity dysregulation.
Rodriguez JA et al.
Chemico-biological Interactions, 2022
Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS-CoV-2 from 946 whole-exome sequencing data in the Turkish population.
Duman N et al.
Journal of Medical Virology, 2022
Characterization of ACE2 naturally occurring missense variants: impact on subcellular localization and trafficking.
Badawi S et al.
Human Genomics, 2022
Angiotensin-Converting Enzyme 2 SNPs as Common Genetic Loci and Optimal Early Identification Genetic Markers for COVID-19.
Ma Y et al.
Pathogens (basel, Switzerland), 2022
The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature.
Ishak A et al.
Gene, 2022
Analysis of the docking property of host variants of hACE2 for SARS-CoV-2 in a large cohort.
Paik H et al.
Plos Computational Biology, 2022
Human ACE2 Polymorphisms from Different Human Populations Modulate SARS-CoV-2 Infection.
Hu P et al.
Viruses, 2022
Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection.
Zhang C et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
Association of polymorphisms in tumor necrosis factors with SARS-CoV-2 infection and mortality rate: A case-control study and in silico analyses.
Heidari Nia M et al.
Journal of Medical Virology, 2022
GSTO1, GSTO2 and ACE2 Polymorphisms Modify Susceptibility to Developing COVID-19.
Djukic T et al.
Journal of Personalized Medicine, 2022
Systematic review of host genetic association with Covid-19 prognosis and susceptibility: What have we learned in 2020?
Ferreira de Araújo JL et al.
Reviews in Medical Virology, 2022
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.
MacGowan SA et al.
Plos Computational Biology, 2022
Polymorphisms and mutations of ACE2 and TMPRSS2 genes are associated with COVID-19: a systematic review.
Li J et al.
European Journal of Medical Research, 2022
Identification of destabilizing SNPs in SARS-CoV2-ACE2 protein and spike glycoprotein: implications for virus entry mechanisms.
Khalid Z et al.
Journal of Biomolecular Structure & Dynamics, 2022
Are angiotensin converting enzyme (ACE1/ACE2) gene variants associated with the clinical severity of COVID-19 pneumonia? A single-center cohort study.
Baştuğ S et al.
Anatolian Journal of Cardiology, 2022
An overview of human proteins and genes involved in SARS-CoV-2 infection.
Jahanafrooz Z et al.
Gene, 2022
Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.
Ren W et al.
Journal of Virology, 2022
SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds.
Vadgama N et al.
Frontiers in Genetics, 2022
Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis.
Dieter C et al.
Plos One, 2022
GDF15 and ACE2 stratify COVID-19 patients according to severity while ACE2 mutations increase infection susceptibility.
Torrens-Mas M et al.
Frontiers in Cellular and Infection Microbiology, 2022
Genetic variations affecting ACE2 protein stability in minority populations.
Mahase V et al.
Frontiers in Medicine, 2022
The role of angiotensin-converting enzyme 2 (ACE2) genetic variations in COVID-19 infection: a literature review.
Fawzy MS et al.
The Egyptian Journal of Medical Human Genetics, 2022
ACE2 polymorphism and susceptibility for SARS-CoV-2 infection and severity of COVID-19.
Möhlendick B et al.
Pharmacogenetics and Genomics, 2021
Human genetic basis of coronavirus disease 2019.
Deng H et al.
Signal Transduction and Targeted Therapy, 2021
Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics.
Barton MI et al.
Elife, 2021
Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.
Zhang C et al.
Medrxiv : the Preprint Server for Health Sciences, 2021
Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.
Zhang C et al.
Research Square, 2021
Hypotheses and facts for genetic factors related to severe COVID-19.
Kotsev SV et al.
World Journal of Virology, 2021