Varaico: Literature-Extracted Genetic Variants

Gene:ACE2
Variant:p.T20N
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ACE2

NM_001371415.1:p.T20N

Associated Papers

Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics.

Waman VP et al.

Scientific Reports, 2024

38902252 (PubMed )
Supplement: 41598_2024_61541_MOESM1_ESM.zip › Supplementary_files_allincludingrevised__13May_2024 › Supplementary_Table_3-_Virus_mutations_mCSM-PPI2_results.xlsx › AXL-NTD

Machine learning-based approach KEVOLVE efficiently identifies SARS-CoV-2 variant-specific genomic signatures.

Lebatteux D et al.

Plos One, 2024

Dynamics of water-mediated interaction effects on the stability and transmission of Omicron.

Zaman N et al.

Scientific Reports, 2023

VarLOCK: sequencing-independent, rapid detection of SARS-CoV-2 variants of concern for point-of-care testing, qPCR pipelines and national wastewater surveillance.

Nan X et al.

Scientific Reports, 2023

Analysis of the N-glycosylation profiles of the spike proteins from the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2.

Wang D et al.

Analytical and Bioanalytical Chemistry, 2023

Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern.

Shajahan A et al.

Scientific Reports, 2023

Whole Sequencing and Detailed Analysis of SARS-CoV-2 Genomes in Southeast Spain: Identification of Recurrent Mutations in the 20E (EU1) Variant with Some Clinical Implications.

López-Andreo MJ et al.

Diseases (basel, Switzerland), 2023

Modelling SARS-CoV-2 spike-protein mutation effects on ACE2 binding.

Thakur S et al.

Journal of Molecular Graphics & Modelling, 2023

36481587 (PubMed )
Supplement: mmc1.docx

Variations within the Glycan Shield of SARS-CoV-2 Impact Viral Spike Dynamics.

Newby ML et al.

Journal of Molecular Biology, 2023

Genomic Analysis of Non-B Nucleic Acids Structures in SARS-CoV-2: Potential Key Roles for These Structures in Mutability, Translation, and Replication?

Bidula S et al.

Genes, 2023

The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants.

Rothenberger S et al.

Nature Biotechnology, 2022

35864170 (PubMed )
Supplement: 41587_2022_1382_MOESM1_ESM.pdf

Site Specific N- and O-glycosylation mapping of the Spike Proteins of SARS-CoV-2 Variants of Concern.

Shajahan A et al.

Research Square, 2022

A comprehensive analysis of the mutational landscape of the newly emerging Omicron (B.1.1.529) variant and comparison of mutations with VOCs and VOIs.

Chakraborty C et al.

Geroscience, 2022

SARS-CoV-2 Variants, Current Vaccines and Therapeutic Implications for COVID-19.

Liang HY et al.

Vaccines, 2022

Aggregation of high-frequency RBD mutations of SARS-CoV-2 with three VOCs did not cause significant antigenic drift.

Li T et al.

Journal of Medical Virology, 2022

35032057 (PubMed )
Supplement: JMV-94-2108-s001.doc

Waves and variants of SARS-CoV-2: understanding the causes and effect of the COVID-19 catastrophe.

Thakur V et al.

Infection, 2022

A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein.

Ghosh N et al.

International Immunopharmacology, 2022

Clinical Characteristics, Transmissibility, Pathogenicity, Susceptible Populations, and Re-infectivity of Prominent COVID-19 Variants.

Yang Z et al.

Aging and Disease, 2022

Genomic surveillance reveals the detection of SARS-CoV-2 delta, beta, and gamma VOCs during the third wave in Pakistan.

Umair M et al.

Journal of Medical Virology, 2022

Longitudinal analysis of SARS-CoV-2 spike and RNA-dependent RNA polymerase protein sequences reveals the emergence and geographic distribution of diverse mutations.

Showers WM et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2022

34801754 (PubMed )
Supplement: mmc2.xlsx › Spike_Variant_Combinations

Inhibitor screening using microarray identifies the high capacity of neutralizing antibodies to Spike variants in SARS-CoV-2 infection and vaccination.

Zhang X et al.

Theranostics, 2022

35401825 (PubMed )
Supplement: thnov12p2519s1.pdf

Deep phylogenetic-based clustering analysis uncovers new and shared mutations in SARS-CoV-2 variants as a result of directional and convergent evolution.

Nunes DR et al.

Plos One, 2022

Role of COVID-19 Vaccines in SARS-CoV-2 Variants.

Zhou Z et al.

Frontiers in Immunology, 2022

Genomic surveillance, evolution and global transmission of SARS-CoV-2 during 2019-2022.

Sharif N et al.

Plos One, 2022

Dynamics of Viral Infection and Evolution of SARS-CoV-2 Variants in the Calabria Area of Southern Italy.

De Marco C et al.

Frontiers in Microbiology, 2022

Structural and energetic analyses of SARS-CoV-2 N-terminal domain characterise sugar binding pockets and suggest putative impacts of variants on COVID-19 transmission.

Lam SD et al.

Computational and Structural Biotechnology Journal, 2022

36408455 (PubMed )
Supplement: mmc1.docx

Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants.

McCallum M et al.

Science (new York, N.y.), 2021

34751595 (PubMed )
Supplement: NIHMS2082814-supplement-Supplementary_materials_all.pdf

SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021.

Alkhatib M et al.

Microbiology Spectrum, 2021

Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity.

Lucas C et al.

Nature, 2021

Structural and functional insights into the spike protein mutations of emerging SARS-CoV-2 variants.

Gupta D et al.

Cellular and Molecular Life Sciences : Cmls, 2021

Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity.

Gong SY et al.

Virology, 2021

34536797 (PubMed )
Supplement: mmc1.pdf

Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization.

Zhang L et al.

Communications Biology, 2021

34645933 (PubMed )
Supplement: 42003_2021_2728_MOESM2_ESM.pdf

Molecular Level Dissection of Critical Spike Mutations in SARS-CoV-2 Variants of Concern (VOCs): A Simplified Review.

Joshi N et al.

Chemistryselect, 2021

Molecular basis of immune evasion by the delta and kappa SARS-CoV-2 variants.

McCallum M et al.

Biorxiv : the Preprint Server for Biology, 2021

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.

Wang R et al.

Immunity, 2021

The Emerging Concern and Interest SARS-CoV-2 Variants.

Janik E et al.

Pathogens (basel, Switzerland), 2021

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants.

Pegu A et al.

Biorxiv : the Preprint Server for Biology, 2021

34031659 (PubMed )
Supplement: NIHPP2021.05.13.444010V1-supplement-1.pdf

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization.

Wang P et al.

Cell Host & Microbe, 2021

Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization.

Wang P et al.

Biorxiv : the Preprint Server for Biology, 2021

Structure-Function Analyses of New SARS-CoV-2 Variants B.1.1.7, B.1.351 and B.1.1.28.1: Clinical, Diagnostic, Therapeutic and Public Health Implications.

Singh J et al.

Viruses, 2021

Evolution, correlation, structural impact and dynamics of emerging SARS-CoV-2 variants.

Spratt AN et al.

Computational and Structural Biotechnology Journal, 2021

Meta-Analysis and Structural Dynamics of the Emergence of Genetic Variants of SARS-CoV-2.

Castonguay N et al.

Frontiers in Microbiology, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."