Associated Papers
PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth.
He X et al.
Molecular Cell, 2025
53BP1-ACLY-SLBP-coordinated activation of replication-dependent histone biogenesis maintains genomic integrity.
Wu T et al.
Nucleic Acids Research, 2022
35037047 (PubMed )
Supplement: gkab1300_supplemental_file.docx
Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells.
Dominguez M et al.
Frontiers in Immunology, 2022
Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.
Sivanand S et al.
Molecular Cell, 2017
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