Varaico: Literature-Extracted Genetic Variants

Gene:ACTB
Variant:p.G245S
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ACTB

NM_001101.5:p.G245S

Associated Papers

A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death.

Ceder S et al.

Embo Molecular Medicine, 2021

33314700 (PubMed )
Supplement: EMMM-13-e10852-s001.pdf

Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.

Wang Z et al.

Molecular Cancer Research : Mcr, 2020

Could Dissimilar Phenotypic Effects of ACTB Missense Mutations Reflect the Actin Conformational Change? Two Novel Mutations and Literature Review.

Sandestig A et al.

Molecular Syndromology, 2019

High Yield of Pathogenic Germline Mutations Causative or Likely Causative of the Cancer Phenotype in Selected Children with Cancer.

Diets IJ et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018

Targeted next-generation sequencing in the diagnosis of neurodevelopmental disorders.

Okamoto N et al.

Clinical Genetics, 2015

Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells.

Tepper CG et al.

The Prostate, 2005

Complex functions of mutant p53 alleles from human prostate cancer.

Shi XB et al.

The Prostate, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."