Varaico: Literature-Extracted Genetic Variants

Gene:ACTB
Variant:p.G13R
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ACTB

NM_001101.5:p.G13R

Associated Papers

Oncometabolite D-2-hydroxyglutarate regulates actin dynamics and nuclear homeostasis in IDH1-mutant glioma.

Lathoria K et al.

Cellular Signalling, 2026

Nuclear actin is a critical regulator of Drosophila female germline stem cell maintenance.

Green NM et al.

Biorxiv : the Preprint Server for Biology, 2024

Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors.

Joshi P et al.

Biomed Research International, 2024

Aggravated Ulcerative Colitis via circNlgn-Mediated Suppression of Nuclear Actin Polymerization.

Du WW et al.

Research (washington, D.c.), 2024

Actin nucleators safeguard replication forks by limiting nascent strand degradation.

Nieminuszczy J et al.

Nucleic Acids Research, 2023

Actin nucleators safeguard replication forks by limiting nascent strand degradation.

Nieminuszczy J et al.

Biorxiv : the Preprint Server for Biology, 2023

Impairment of nuclear F-actin formation and its relevance to cellular phenotypes in Hutchinson-Gilford progeria syndrome.

Takahashi Y et al.

Nucleus (austin, Tex.), 2020

Nuclear Actin: From Discovery to Function.

Kelpsch DJ et al.

Anatomical Record (hoboken, N.j. : 2007), 2018

Nuclear F-actin enhances the transcriptional activity of β-catenin by increasing its nuclear localization and binding to chromatin.

Yamazaki S et al.

Histochemistry and Cell Biology, 2016

Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear.

Drummond MC et al.

Nature Communications, 2015

Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes.

Miyamoto K et al.

Genes & Development, 2011

Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL.

Posern G et al.

The Embo Journal, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."