Associated Papers
Haploinsufficiency and Alzheimer's Disease: The Possible Pathogenic and Protective Genetic Factors.
Bagyinszky E et al.
International Journal of Molecular Sciences, 2024
Osteomesopyknosis associated with a novel ALOX5 variant that impacts the RANKL pathway.
Fernandez-Luna JL et al.
Molecular Genetics & Genomic Medicine, 2024
Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma.
Patiño-García A et al.
Ebiomedicine, 2024
The role of genetic risk factors of Alzheimer's disease in synaptic dysfunction.
Fu WY et al.
Seminars in Cell & Developmental Biology, 2023
ADAM10 Gene Variants in AD Patients and Their Relationship to CSF Protein Levels.
Agüero-Rabes P et al.
International Journal of Molecular Sciences, 2023
AmazonForest: In Silico Metaprediction of Pathogenic Variants.
Palheta HGA et al.
Biology, 2022
A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects.
Acosta-Uribe J et al.
Genome Medicine, 2022
Challenge accepted: uncovering the role of rare genetic variants in Alzheimer's disease.
Khani M et al.
Molecular Neurodegeneration, 2022
Genomics and Functional Genomics of Alzheimer's Disease.
Kamboh MI
Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics, 2022
Sulfuretin exerts diversified functions in the processing of amyloid precursor protein.
Chen J et al.
Genes & Diseases, 2021
α-Secretase nonsense mutation (ADAM10 Tyr167*) in familial Alzheimer's disease.
Agüero P et al.
Alzheimer's Research & Therapy, 2020
Substrate-Specific Activation of α-Secretase by 7-Deoxy-Trans-Dihydronarciclasine Increases Non-Amyloidogenic Processing of β-Amyloid Protein Precursor.
Chun YS et al.
Molecules (basel, Switzerland), 2020
Protein-protein interactions underlying the behavioral and psychological symptoms of dementia (BPSD) and Alzheimer's disease.
Mao Y et al.
Plos One, 2020
Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation.
Hildebrandt MR et al.
Stem Cell Reports, 2019
Untangling Genetic Risk for Alzheimer's Disease.
Pimenova AA et al.
Biological Psychiatry, 2018
Genetic underpinnings in Alzheimer's disease - a review.
Moustafa AA et al.
Reviews in the Neurosciences, 2018
The genetic landscape of Alzheimer disease.
Carmona S et al.
Handbook of Clinical Neurology, 2018
Molecular Genetics of Neurodegenerative Dementias.
Hinz FI et al.
Cold Spring Harbor Perspectives in Biology, 2017
Monoaminergic neuropathology in Alzheimer's disease.
Šimić G et al.
Progress in Neurobiology, 2017
State of Play in Alzheimer's Disease Genetics.
Zhu JB et al.
Journal of Alzheimer's Disease : Jad, 2017
Alzheimer's Disease: From Genetic Variants to the Distinct Pathological Mechanisms.
Sun Q et al.
Frontiers in Molecular Neuroscience, 2017
Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.
Molnár J et al.
Plos One, 2016
Mapping Breakpoints of Complex Chromosome Rearrangements Involving a Partial Trisomy 15q23.1-q26.2 Revealed by Next Generation Sequencing and Conventional Techniques.
Pan Q et al.
Plos One, 2016
Genes associated with Alzheimer's disease: an overview and current status.
Giri M et al.
Clinical Interventions in Aging, 2016
Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns.
Zhang W et al.
Stem Cells International, 2016
Genetic diagnosis and prognosis of Alzheimer's disease: challenges and opportunities.
Reitz C
Expert Review of Molecular Diagnostics, 2015
Alzheimer's disease risk genes and mechanisms of disease pathogenesis.
Karch CM et al.
Biological Psychiatry, 2015
Additional mechanisms conferring genetic susceptibility to Alzheimer's disease.
Calero M et al.
Frontiers in Cellular Neuroscience, 2015
Alzheimer's disease genetics: from the bench to the clinic.
Karch CM et al.
Neuron, 2014
Clinical genetics of Alzheimer's disease.
Zou Z et al.
Biomed Research International, 2014
Identification of rare variants in Alzheimer's disease.
Lord J et al.
Frontiers in Genetics, 2014
ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function.
Suh J et al.
Neuron, 2013
ADAM10 prodomain mutations cause late-onset Alzheimer's disease: not just the latest FAD.
Vassar R
Neuron, 2013
A brief history of Alzheimer's disease gene discovery.
Tanzi RE
Journal of Alzheimer's Disease : Jad, 2013
The genetics of Alzheimer disease.
Tanzi RE
Cold Spring Harbor Perspectives in Medicine, 2012
The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE.
Guerreiro RJ et al.
Neurobiology of Aging, 2012
Evidence against a role for rare ADAM10 mutations in sporadic Alzheimer disease.
Cai G et al.
Neurobiology of Aging, 2012
Genetic association between ADAM10 gene polymorphism and Alzheimer's disease in a Northern Han Chinese population.
Song JH et al.
Brain Research, 2011
Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease.
Bekris LM et al.
Neurobiology of Aging, 2011
Genetics and biology of Alzheimer's disease and frontotemporal lobar degeneration.
Galimberti D et al.
International Journal of Clinical and Experimental Medicine, 2010
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.
Kim M et al.
Human Molecular Genetics, 2009
Computational analysis and molecular dynamics simulation of high-risk single nucleotide polymorphisms of the ADAM10 gene.
Namme JN et al.
Journal of Biomolecular Structure & Dynamics, 0