Varaico: Literature-Extracted Genetic Variants

Gene:ADAM17
Variant:p.M435L
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ADAM17

NM_003183.6:p.M435L

Associated Papers

Substitution of methionine 435 with leucine, isoleucine, and serine in tumor necrosis factor alpha converting enzyme inactivates ectodomain shedding activity.

Pérez L et al.

Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."