Varaico: Literature-Extracted Genetic Variants

Gene:ADAMTS10
Variant:p.G661R
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ADAMTS10

NM_030957.4:p.G661R

Associated Papers

The Biomechanics of Fibrillin Microfibrils: Lessons from the Ciliary Zonule.

Rathaur P et al.

Cells, 2024

Assessment of Early Glaucomatous Optic Neuropathy in the Dog by Spectral Domain Optical Coherence Tomography (SD-OCT).

Oh A et al.

Micromachines, 2024

Exclusion of previously described variant in LTBP2 for primary glaucoma in Australian Burmese cats.

Ranocchia J et al.

Animal Genetics, 2023

Optic neuropathy associated with TGFβ dysregulation in mice with a glaucoma-causative mutation of ADAMTS10.

Wu HJ et al.

Matrix Biology : Journal of the International Society for Matrix Biology, 2022

A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels.

Gomes FE et al.

American Journal of Veterinary Research, 2022

Adamts10 controls transforming growth factor β family signaling that contributes to retinal ganglion cell development.

Wareham LK et al.

Frontiers in Molecular Biosciences, 2022

Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10.

Wu HJ et al.

Investigative Ophthalmology & Visual Science, 2021

Biomechanics of the optic nerve head and sclera in canine glaucoma: A brief review.

Park SA et al.

Veterinary Ophthalmology, 2021

Evaluation of ADAMTS17 in Chinese Shar-Pei with primary open-angle glaucoma, primary lens luxation, or both.

Oliver JAC et al.

American Journal of Veterinary Research, 2018

Genetic and Biochemical Biomarkers in Canine Glaucoma.

Graham KL et al.

Veterinary Pathology, 2017

ABCB1 variants confer susceptibility to primary open-angle glaucoma and predict individual differences to latanoprost treatment.

Liu H et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2016

A novel missense mutation in ADAMTS10 in Norwegian Elkhound primary glaucoma.

Ahonen SJ et al.

Plos One, 2014

The genetics of eye disorders in the dog.

Mellersh CS

Canine Genetics and Epidemiology, 2014

Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles.

Kuchtey J et al.

Investigative Ophthalmology & Visual Science, 2013

Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk.

Kanemaki N et al.

Plos One, 2013

Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function.

Hubmacher D et al.

Cellular and Molecular Life Sciences : Cmls, 2011

Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.

Kuchtey J et al.

Plos Genetics, 2011

The microfibril hypothesis of glaucoma: implications for treatment of elevated intraocular pressure.

Kuchtey J et al.

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."