Associated Papers
Heterozygous ADAR mutant mice exhibit RNA sensing-dependent neuroinflammation and phenotypes associated with Aicardi-Goutières syndrome.
Guo X et al.
Iscience, 2026
Biochemical profiling and structural basis of ADAR1-mediated RNA editing.
Deng X et al.
Molecular Cell, 2025
Structural impacts of two disease-linked ADAR1 mutants: a molecular dynamics study.
Huang WC et al.
Journal of Computer-aided Molecular Design, 2024
Novel insights into double-stranded RNA-mediated immunopathology.
de Reuver R et al.
Nature Reviews. Immunology, 2024
Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1.
Karki A et al.
Biochemistry, 2024
The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways.
Nakahama T et al.
International Immunology, 2023
The role of RNA editing enzyme ADAR1 in human disease.
Song B et al.
Wiley Interdisciplinary Reviews. Rna, 2022
Deciphering the Biological Significance of ADAR1-Z-RNA Interactions.
Nakahama T et al.
International Journal of Molecular Sciences, 2021
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes.
Galka-Marciniak P et al.
Nucleic Acids Research, 2021
RNA Editing in Interferonopathies.
Frassinelli L et al.
Methods in Molecular Biology (clifton, N.j.), 2021
Adenosine-to-inosine RNA editing in the immune system: friend or foe?
Nakahama T et al.
Cellular and Molecular Life Sciences : Cmls, 2020
Sources of discordance among germ-line variant classifications in ClinVar.
Yang S et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017
Genetic, Phenotypic, and Interferon Biomarker Status in ADAR1-Related Neurological Disease.
Rice GI et al.
Neuropediatrics, 2017
Effects of Aicardi-Goutières syndrome mutations predicted from ADAR-RNA structures.
Fisher AJ et al.
Rna Biology, 2017
Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.
Crow YJ et al.
American Journal of Medical Genetics. Part A, 2015
Diverse selective regimes shape genetic diversity at ADAR genes and at their coding targets.
Forni D et al.
Rna Biology, 2015
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Rice GI et al.
Nature Genetics, 2012