Associated Papers
Biochemical profiling and structural basis of ADAR1-mediated RNA editing.
Deng X et al.
Molecular Cell, 2025
Structural impacts of two disease-linked ADAR1 mutants: a molecular dynamics study.
Huang WC et al.
Journal of Computer-aided Molecular Design, 2024
Novel insights into double-stranded RNA-mediated immunopathology.
de Reuver R et al.
Nature Reviews. Immunology, 2024
Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1.
Karki A et al.
Biochemistry, 2024
A Novel Mutation of the ADAR1 Gene in a Chinese Family with Dyschromatosis Symmetrica Hereditaria and Literature Review.
Ge H et al.
Clinical, Cosmetic and Investigational Dermatology, 2024
The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways.
Nakahama T et al.
International Immunology, 2023
The role of RNA editing enzyme ADAR1 in human disease.
Song B et al.
Wiley Interdisciplinary Reviews. Rna, 2022
Deciphering the Biological Significance of ADAR1-Z-RNA Interactions.
Nakahama T et al.
International Journal of Molecular Sciences, 2021
ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.
de Reuver R et al.
Cell Reports, 2021
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes.
Galka-Marciniak P et al.
Nucleic Acids Research, 2021
RNA Editing in Interferonopathies.
Frassinelli L et al.
Methods in Molecular Biology (clifton, N.j.), 2021
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.
Cao Y et al.
Cell Research, 2020
Adenosine-to-inosine RNA editing in the immune system: friend or foe?
Nakahama T et al.
Cellular and Molecular Life Sciences : Cmls, 2020
Seven novel mutations of ADAR in multi-ethnic pedigrees with dyschromatosis symmetrica hereditaria in China.
Wang P et al.
Molecular Genetics & Genomic Medicine, 2019
Sources of discordance among germ-line variant classifications in ClinVar.
Yang S et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017
Genetic, Phenotypic, and Interferon Biomarker Status in ADAR1-Related Neurological Disease.
Rice GI et al.
Neuropediatrics, 2017
Effects of Aicardi-Goutières syndrome mutations predicted from ADAR-RNA structures.
Fisher AJ et al.
Rna Biology, 2017
Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity.
Matthews MM et al.
Nature Structural & Molecular Biology, 2016
Global Carrier Rates of Rare Inherited Disorders Using Population Exome Sequences.
Fujikura K
Plos One, 2016
Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.
Crow YJ et al.
American Journal of Medical Genetics. Part A, 2015
ADAR1 Facilitates HIV-1 Replication in Primary CD4+ T Cells.
Cuadrado E et al.
Plos One, 2015
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Rice GI et al.
Nature Genetics, 2012