Varaico: Literature-Extracted Genetic Variants

Gene:ADARB1
Variant:p.E396A
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ADARB1

NM_001112.4:p.E396A

Associated Papers

RNA modifications, alternative splicing and circular RNA landscape in the mouse brain: inosine and beyond.

Larrea E et al.

Scientific Reports, 2025

C to U RNA editing of MFN1 is regulated by ADARB1 and associates with favourable prognosis in chronic lymphocytic leukemia.

Gonzalez Martinez A et al.

Scientific Reports, 2025

A-to-I-Edited miR-1304-3p Inhibits Glycolysis and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inactivating Wnt5a/ROR2 Signaling.

Chen P et al.

Molecular Carcinogenesis, 2025

Small nucleolar RNA host gene 18 controls vascular smooth muscle cell contractile phenotype and neointimal hyperplasia.

Niu K et al.

Cardiovascular Research, 2024

Multifaceted role of RNA editing in promoting loss-of-function of PODXL in cancer.

Fu T et al.

Iscience, 2022

ADAR1 and its implications in cancer development and treatment.

Baker AR et al.

Trends in Genetics : Tig, 2022

RNA binding candidates for human ADAR3 from substrates of a gain of function mutant expressed in neuronal cells.

Wang Y et al.

Nucleic Acids Research, 2019

Tumor-associated intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation.

Chen YT et al.

The Journal of Biological Chemistry, 2018

The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer.

Shelton PM et al.

Cell Reports, 2018

Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy.

Wettengel J et al.

Nucleic Acids Research, 2017

Probing RNA recognition by human ADAR2 using a high-throughput mutagenesis method.

Wang Y et al.

Nucleic Acids Research, 2016

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer.

Chan TH et al.

Gastroenterology, 2016

Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons.

Yamashita T et al.

Embo Molecular Medicine, 2013

A screening protocol for identification of functional mutants of RNA editing adenosine deaminases.

Eifler T et al.

Current Protocols in Chemical Biology, 2012

Deficiency in RNA editing enzyme ADAR2 impairs regulated exocytosis.

Yang L et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2010

Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2.

Singh M et al.

The Journal of Biological Chemistry, 2007

The C-terminal domain of RNA Pol II helps ensure that editing precedes splicing of the GluR-B transcript.

Ryman K et al.

Rna (new York, N.y.), 2007

ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells.

Yang W et al.

The Journal of Biological Chemistry, 2005

Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA.

Cho DS et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."