Varaico: Literature-Extracted Genetic Variants

Gene:ADH1B
Variant:p.R370C
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ADH1B

NM_000668.6:p.R370C

Associated Papers

Whole-exome sequencing in children with dyslexia implicates rare variants in CLDN3 and ion channel genes.

Marianski K et al.

Human Genetics, 2025

41442065 (PubMed )
Supplement: 439_2025_2796_MOESM4_ESM.xlsx › ST2

A Mendelian randomization study of alcohol use and cardiometabolic disease risk in a multi-ancestry population from the Million Veteran Program.

Kember RL et al.

Alcohol, Clinical & Experimental Research, 2024

Improving the discovery of rare variants associated with alcohol problems by leveraging machine learning phenotype prediction and functional information.

Ahangari M et al.

Biorxiv : the Preprint Server for Biology, 2023

Genetic Influences on Fetal Alcohol Spectrum Disorder.

Sambo D et al.

Genes, 2023

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Valentine H et al.

Cancer Research Communications, 2022

36643868 (PubMed )
Supplement: crc-22-0245-s07.xlsx › Variants_All_Exonic.exclude_ncR

Positive selection acts on regulatory genetic variants in populations of European ancestry that affect ALDH2 gene expression.

Schaschl H et al.

Scientific Reports, 2022

Exploring the Role of Alcohol Metabolizing Genotypes in a 12-Week Clinical Trial of Naltrexone for Alcohol Use Disorder.

Castaldelli-Maia JM et al.

Biomolecules, 2021

Genetic Variants of Alcohol Metabolizing Enzymes and Alcohol-Related Liver Cirrhosis Risk.

Ayuso P et al.

Journal of Personalized Medicine, 2021

The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.

Cao Y et al.

Cell Research, 2020

32355288 (PubMed )
Supplement: 41422_2020_322_MOESM20_ESM.xlsx › S13

Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China.

Zhang C et al.

Molecular Genetics & Genomic Medicine, 2019

Alcohol-metabolizing Enzymes' Gene Polymorphisms and Susceptibility to Multiple Head and Neck Cancers.

Chien HT et al.

Cancer Prevention Research (philadelphia, Pa.), 2019

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Walters RK et al.

Nature Neuroscience, 2018

ADH1B: From alcoholism, natural selection, and cancer to the human phenome.

Polimanti R et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2018

Analysis of the Association of Nonsynonymous Polymorphisms in ADH Genes with Hazardous Drinking in HIV-1-Positive Individuals.

Wolf JM et al.

Alcoholism, Clinical and Experimental Research, 2017

Investigating the Association between Alcohol and Risk of Head and Neck Cancer in Taiwan.

Huang CC et al.

Scientific Reports, 2017

Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk.

Sakiyama M et al.

Scientific Reports, 2017

The allele frequency of ALDH2*Glu504Lys and ADH1B*Arg47His for the Ryukyu islanders and their history of expansion among East Asians.

Koganebuchi K et al.

American Journal of Human Biology : the Official Journal of the Human Biology Council, 2017

Genetic polymorphisms study of pharmacogenomic VIP variants in Han ethnic of China's Shaanxi province.

Jin T et al.

Environmental Toxicology and Pharmacology, 2016

Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?

Hart AB et al.

Addiction Biology, 2016

Genetic polymorphisms of pharmacogenomic VIP variants in the Mongol of Northwestern China.

Jin T et al.

Bmc Genetics, 2016

Genetic Polymorphisms Analysis of Pharmacogenomic VIP Variants in Miao Ethnic Group of Southwest China.

Jin T et al.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 2015

Genetic polymorphisms in very important pharmacogenomic (VIP) variants in the Tibetan population.

Jin TB et al.

Genetics and Molecular Research : Gmr, 2015

Natural variability of minimotifs in 1092 people indicates that minimotifs are targets of evolution.

Lyon KF et al.

Nucleic Acids Research, 2015

Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans.

Xu K et al.

Alcoholism, Clinical and Experimental Research, 2015

Genetic polymorphisms of pharmacogenomic VIP variants in the Uygur population from northwestern China.

Wang L et al.

Bmc Genetics, 2015

The joint effects of ADH1B variants and childhood adversity on alcohol related phenotypes in African-American and European-American women and men.

Sartor CE et al.

Alcoholism, Clinical and Experimental Research, 2014

Genetic influences on response to alcohol and response to pharmacotherapies for alcoholism.

Enoch MA

Pharmacology, Biochemistry, and Behavior, 2014

Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study.

Dura P et al.

Journal of Human Genetics, 2013

Genetic influences on the development of alcoholism.

Enoch MA

Current Psychiatry Reports, 2013

Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism.

Zuo L et al.

Human Genetics, 2013

ADH1C Ile350Val polymorphism and cancer risk: evidence from 35 case-control studies.

Xue Y et al.

Plos One, 2012

Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases.

Li D et al.

Biological Psychiatry, 2011

Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations.

Liu J et al.

Alcoholism, Clinical and Experimental Research, 2011

Combined effect of ADH1B RS1229984, RS2066702 and ADH1C RS1693482/ RS698 alleles on alcoholism and chronic liver diseases.

Tóth R et al.

Disease Markers, 2011

Phenotype prediction of deleterious nonsynonymous single nucleotide polymorphisms in human alcohol metabolism-related genes: a bioinformatics study.

Wang LL et al.

Alcohol (fayetteville, N.y.), 2010

Variability in ethanol biodisposition in whites is modulated by polymorphisms in the ADH1B and ADH1C genes.

Martínez C et al.

Hepatology (baltimore, Md.), 2010

Review of studies on metabolic genes and cancer in populations of African descent.

Ragin CC et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2010

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.

Birley AJ et al.

Human Molecular Genetics, 2009

Coding and non-coding polymorphisms in alcohol dehydrogenase alters protein expression and alcohol-associated erythema.

Pershing LK et al.

The Journal of Investigative Dermatology, 2008

Impact of the alcohol-dehydrogenase (ADH) 1C and ADH1B polymorphisms on drinking behavior in nonalcoholic Japanese.

Matsuo K et al.

Human Mutation, 2007

Effects of natural selection on interpopulation divergence at polymorphic sites in human protein-coding Loci.

Hughes AL et al.

Genetics, 2005

Rare ADH variant constellations are specific for alcohol dependence.

Zuo L et al.

Alcohol and Alcoholism (oxford, Oxfordshire), 0

Genome-wide association discoveries of alcohol dependence.

Zuo L et al.

The American Journal on Addictions, 0

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