Associated Papers
Germline mutations and somatic mosaicism in steatotic liver diseases and related liver carcinogenesis.
Trépo E et al.
Nature Reviews. Gastroenterology & Hepatology, 2026
Genetic Variants in Liver Cirrhosis: Classifications, Mechanisms, and Implications for Clinical Practice.
Raghavan RP et al.
Journal of Personalized Medicine, 2026
Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways.
Vujkovic M et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Role of genetic variants and DNA methylation of lipid metabolism-related genes in metabolic dysfunction-associated steatotic liver disease.
Wang JJ et al.
Frontiers in Physiology, 2025
Genetics of Metabolic Dysfunction-associated Steatotic Liver Disease: The State of the Art Update.
Sookoian S et al.
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association, 2024
A genome-wide association analysis reveals new pathogenic pathways in gout.
Major TJ et al.
Nature Genetics, 2024
The contribution of genetics and epigenetics to MAFLD susceptibility.
Moretti V et al.
Hepatology International, 2024
Population-specific putative causal variants shape quantitative traits.
Koyama S et al.
Nature Genetics, 2024
Human genetics and epigenetics of alcohol use disorder.
Zhou H et al.
The Journal of Clinical Investigation, 2024
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.
Ghouse J et al.
Nature Genetics, 2024
Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people.
Koyanagi YN et al.
Science Advances, 2024
Complex effects of sequence variants on lipid levels and coronary artery disease.
Snaebjarnarson AS et al.
Cell, 2023
Mediation analysis unveils a carcinogenic effect of ADH1B rs1229984 through mechanisms other than change in drinking intensity: oesophageal cancer case-control study.
Sugimoto Y et al.
Japanese Journal of Clinical Oncology, 2023
Large-scale genome sequencing redefines the genetic footprints of high-altitude adaptation in Tibetans.
Zheng W et al.
Genome Biology, 2023
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Kanoni S et al.
Genome Biology, 2022
Gene polymorphisms of cyclin-dependent kinase inhibitor and matrix metalloproteinase-9 in Sudanese patients with esophageal squamous cell carcinoma.
Eltayeb MM et al.
Molecular Genetics & Genomic Medicine, 2022
Multiomics study of nonalcoholic fatty liver disease.
Sveinbjornsson G et al.
Nature Genetics, 2022
Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.
Valentine H et al.
Cancer Research Communications, 2022
Genetic susceptibility of bladder cancer in the Lebanese population.
Kourie HR et al.
Bmc Medical Genomics, 2022
SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.
O'Brien NL et al.
Alcohol and Alcoholism (oxford, Oxfordshire), 2022
Genetic Variations of ALDH (rs671) Are Associated With the Persistence of HBV Infection Among the Chinese Han Population.
Shang D et al.
Frontiers in Medicine, 2022
Machine learning enables new insights into genetic contributions to liver fat accumulation.
Haas ME et al.
Cell Genomics, 2021
Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays.
Khoruddin NA et al.
Scientific Reports, 2021
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.
Akbari P et al.
Science (new York, N.y.), 2021
Genetic Variants of Alcohol Metabolizing Enzymes and Alcohol-Related Liver Cirrhosis Risk.
Ayuso P et al.
Journal of Personalized Medicine, 2021
Functional and clinical implications of genetic structure in 1686 Italian exomes.
Birolo G et al.
Human Mutation, 2021
Association Study of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Polymorphism With Alzheimer Disease in the Taiwanese Population.
Wu YY et al.
Frontiers in Neuroscience, 2021
Identification of New Tumor-Related Gene Mutations in Chinese Gastrointestinal Stromal Tumors.
Feng Y et al.
Frontiers in Cell and Developmental Biology, 2021
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Surendran P et al.
Nature Genetics, 2020
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.
Cao Y et al.
Cell Research, 2020
A deep analysis using panel-based next-generation sequencing in an Ecuadorian pediatric patient with anaplastic astrocytoma: a case report.
García-Cárdenas JM et al.
Journal of Medical Case Reports, 2020
Cumulative Evidence for Associations between Genetic Variants and Risk of Esophageal Cancer.
Li G et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2020
Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population.
Sakaue S et al.
European Journal of Human Genetics : Ejhg, 2020
No genetic evidence for involvement of alcohol dehydrogenase genes in risk for Parkinson's disease.
Kim JJ et al.
Neurobiology of Aging, 2020
Monitoring treatment efficacy and resistance in breast cancer patients via circulating tumor DNA genomic profiling.
Chen Z et al.
Molecular Genetics & Genomic Medicine, 2020
Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison.
Sun Y et al.
Translational Psychiatry, 2019
Genetic variants of alcohol-metabolizing enzymes in Brugada syndrome: Insights into syncope after drinking alcohol.
Wu Q et al.
Journal of Arrhythmia, 2019