Varaico: Literature-Extracted Genetic Variants

Gene:ADH1C
Variant:p.R272Q
Back to variants list

ADH1C

NM_000669.5:p.R272Q

Associated Papers

Genetic and epigenetic determinants of fetal alcohol spectrum disorders: Toward a precision medicine approach.

Sessa F et al.

Experimental and Molecular Pathology, 2025

Genetic Variants of Alcohol Metabolizing Enzymes and Alcohol-Related Liver Cirrhosis Risk.

Ayuso P et al.

Journal of Personalized Medicine, 2021

Alcohol-metabolizing Enzymes' Gene Polymorphisms and Susceptibility to Multiple Head and Neck Cancers.

Chien HT et al.

Cancer Prevention Research (philadelphia, Pa.), 2019

Association of the alcohol dehydrogenase gene polymorphism rs1789891 with gray matter brain volume, alcohol consumption, alcohol craving and relapse risk.

Bach P et al.

Addiction Biology, 2019

Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics.

John SE et al.

Scientific Reports, 2018

Alcohol intake, ADH1B and ADH1C genotypes, and the risk of colorectal cancer by sex and subsite in the Netherlands Cohort Study.

Offermans NSM et al.

Carcinogenesis, 2018

Analysis of the Association of Nonsynonymous Polymorphisms in ADH Genes with Hazardous Drinking in HIV-1-Positive Individuals.

Wolf JM et al.

Alcoholism, Clinical and Experimental Research, 2017

Effect of single-nucleotide polymorphisms in ADH1B, ADH4, ADH1C, OPRM1, DRD2, BDNF, and ALDH2 genes on alcohol dependence in a Caucasian population.

Katsarou MS et al.

Pharmacology Research & Perspectives, 2017

Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.

Treutlein J et al.

Genes, 2017

Molecular Guided Therapy Provides Sustained Clinical Response in Refractory Choroid Plexus Carcinoma.

Cornelius A et al.

Frontiers in Pharmacology, 2017

28993730 (PubMed )
Supplement: Table3.xlsx › Germline

Polymorphisms in alcohol and tobacco metabolism genes in head and neck cancer in the Basque Country.

Bediaga NG et al.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2015

Association between ADH1B and ADH1C polymorphisms and the risk of head and neck squamous cell carcinoma.

Ji YB et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2015

Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population.

Way M et al.

Addiction Biology, 2015

The alcohol dehydrogenase 1C(rs698) genotype and breast cancer: a meta-analysis.

Mao Q et al.

Asia-pacific Journal of Public Health, 2015

Identification of SNPs associated with response of breast cancer patients to neoadjuvant chemotherapy in the EORTC-10994 randomized phase III trial.

Le Morvan V et al.

The Pharmacogenomics Journal, 2015

XomAnnotate: Analysis of Heterogeneous and Complex Exome- A Step towards Translational Medicine.

Talukder AK et al.

Plos One, 2015

25905921 (PubMed )
Supplement: pone.0123569.s008.xls › BC10_ERR166335

Genetic variation in alcohol metabolizing enzymes among Inuit and its relation to drinking patterns.

Bjerregaard P et al.

Drug and Alcohol Dependence, 2014

The Genetics, Neurogenetics and Pharmacogenetics of Addiction.

Demers CH et al.

Current Behavioral Neuroscience Reports, 2014

Role of UGT1A1 and ADH gene polymorphisms in pegvisomant-induced liver toxicity in acromegalic patients.

Filopanti M et al.

European Journal of Endocrinology, 2014

Genetics of alcohol dependence: a review of clinical studies.

Samochowiec J et al.

Neuropsychobiology, 2014

Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study.

Dura P et al.

Journal of Human Genetics, 2013

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.

Park BL et al.

Human Genetics, 2013

Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C.

Biernacka JM et al.

Plos One, 2013

Genetic association between obstructive bronchitis and enzymes of oxidative stress.

Bauer M et al.

Metabolism: Clinical and Experimental, 2012

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.

Frank J et al.

Addiction Biology, 2012

ADH1C Ile350Val polymorphism and cancer risk: evidence from 35 case-control studies.

Xue Y et al.

Plos One, 2012

The genetics of substance dependence.

Wang JC et al.

Annual Review of Genomics and Human Genetics, 2012

Genetic polymorphisms of ADH1C and CYP2E1 and risk of oral squamous cell carcinoma.

Brocic M et al.

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-head and Neck Surgery, 2011

Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations.

Liu J et al.

Alcoholism, Clinical and Experimental Research, 2011

Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

Wakai K et al.

Journal of Epidemiology, 2011

Combined effect of ADH1B RS1229984, RS2066702 and ADH1C RS1693482/ RS698 alleles on alcoholism and chronic liver diseases.

Tóth R et al.

Disease Markers, 2011

Phenotype prediction of deleterious nonsynonymous single nucleotide polymorphisms in human alcohol metabolism-related genes: a bioinformatics study.

Wang LL et al.

Alcohol (fayetteville, N.y.), 2010

Variability in ethanol biodisposition in whites is modulated by polymorphisms in the ADH1B and ADH1C genes.

Martínez C et al.

Hepatology (baltimore, Md.), 2010

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.

Birley AJ et al.

Human Molecular Genetics, 2009

Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis.

Macgregor S et al.

Human Molecular Genetics, 2009

Impact of alcohol consumption with polymorphisms in alcohol-metabolizing enzymes on pancreatic cancer risk in Japanese.

Kanda J et al.

Cancer Science, 2009

Coding and non-coding polymorphisms in alcohol dehydrogenase alters protein expression and alcohol-associated erythema.

Pershing LK et al.

The Journal of Investigative Dermatology, 2008

Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract.

Hashibe M et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006

Japanese single nucleotide polymorphism database for 267 possible drug-related genes.

Iida A et al.

Cancer Science, 2006

[SNP collection, pharmacogenomics, and the future of drug therapy].

Iida A et al.

Gan to Kagaku Ryoho. Cancer & Chemotherapy, 2002

Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide adenine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families.

Iida A et al.

Journal of Human Genetics, 2001

Rare ADH variant constellations are specific for alcohol dependence.

Zuo L et al.

Alcohol and Alcoholism (oxford, Oxfordshire), 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."