Varaico: Literature-Extracted Genetic Variants

Gene:ADRA1B
Variant:p.D125A
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ADRA1B

NM_000679.4:p.D125A

Associated Papers

Asp125 and Thr130 in transmembrane domain 3 are major sites of alpha1b-adrenergic receptor antagonist binding.

Takahashi K et al.

Biological & Pharmaceutical Bulletin, 2007

Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint.

Porter JE et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."