Varaico: Literature-Extracted Genetic Variants

Gene:ADRA1B
Variant:p.C128F
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ADRA1B

NM_000679.4:p.C128F

Associated Papers

Overexpression of the alpha1B-adrenergic receptor causes apoptotic neurodegeneration: multiple system atrophy.

Zuscik MJ et al.

Nature Medicine, 2000

Dominant-negative activity of an alpha(1B)-adrenergic receptor signal-inactivating point mutation.

Chen S et al.

The Embo Journal, 2000

Constitutive activation of the delta opioid receptor by mutations in transmembrane domains III and VII.

Befort K et al.

The Journal of Biological Chemistry, 1999

Identification of a conserved switch residue responsible for selective constitutive activation of the beta2-adrenergic receptor.

Zuscik MJ et al.

The Journal of Biological Chemistry, 1998

Synergism of constitutive activity in alpha 1-adrenergic receptor activation.

Hwa J et al.

Biochemistry, 1997

Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint.

Porter JE et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."