Associated Papers
In Vitro Mutational Analysis of the β2 Adrenergic Receptor, an In Vivo Surrogate Odorant Receptor.
Jamet S et al.
Plos One, 2015
Understanding the effects on constitutive activation and drug binding of a D130N mutation in the β2 adrenergic receptor via molecular dynamics simulation.
Zhu Y et al.
Journal of Molecular Modeling, 2014
Constitutive activation of the opioid receptor-like (ORL1) receptor by mutation of Asn133 to tryptophan in the third transmembrane region.
Kam KW et al.
Journal of Neurochemistry, 2002
Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.
Ballesteros JA et al.
The Journal of Biological Chemistry, 2001
Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6.
Rasmussen SG et al.
Molecular Pharmacology, 1999
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