Varaico: Literature-Extracted Genetic Variants

Gene:AFP
Variant:p.Q588Q
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AFP

NM_001134.3:p.Q588Q

Associated Papers

The dynamic variation position and predominant quasispecies of hepatitis B virus: Novel predictors of early hepatocarcinoma.

Zhang C et al.

Virus Research, 2024

Distribution and Clinical Significance of Hepatitis B virus A1762T/G1764A Double Mutation in Chronic Hepatitis B Patients: A Cross-Sectional Study.

Changsri K et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2024

HLA-DR genetic polymorphisms and hepatitis B virus mutations affect the risk of hepatocellular carcinoma in Han Chinese population.

Zhao Y et al.

Virology Journal, 2023

The genetic polymorphism down-regulating HLA-DRB1 enhancer activity facilitates HBV persistence, evolution and hepatocarcinogenesis in the Chinese Han population.

Deng Y et al.

Journal of Viral Hepatitis, 2020

Pre-S/Surface and Core Promoter/Precore Mutations in Chronic Hepatitis B Patients with Severe Acute Exacerbation.

Chen YH et al.

Digestive Diseases and Sciences, 2019

Analysis of hepatitis B virus genotype and gene mutation in patients with advanced liver disease in East Kalimantan, Indonesia.

Wahyuni RM et al.

Biomedical Reports, 2019

The mutation of hepatitis B virus and the prognosis of hepatocellular carcinoma after surgery: a pilot study.

Zhang Y et al.

Cancer Management and Research, 2018

Complete genome sequencing and clinical analysis of intrahepatic hepatitis B virus cccDNA from HCC.

Jiao F et al.

Microbial Pathogenesis, 2017

Potential Susceptibility Mutations in C Gene for Hepatitis B-Related Hepatocellular Carcinoma Identified by a Two-Stage Study in Qidong, China.

Qu L et al.

International Journal of Molecular Sciences, 2016

Naturally occurring basal core promoter A1762T/G1764A dual mutations increase the risk of HBV-related hepatocellular carcinoma: a meta-analysis.

Yang Z et al.

Oncotarget, 2016

Hepatitis B virus genotype, mutations, human leukocyte antigen polymorphisms and their interactions in hepatocellular carcinoma: a multi-centre case-control study.

Wen J et al.

Scientific Reports, 2015

The incidence rate over 10 years of naturally occurring, cancer related mutations in the basal core promoter of hepatitis B virus.

Wang XY et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2015

Higher lifetime chance of spontaneous surface antigen loss in hepatitis B carriers with genotype C infection.

Tseng TC et al.

Alimentary Pharmacology & Therapeutics, 2015

Association of a potential functional pre-miR-218 polymorphism and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk.

Han Y et al.

Liver International : Official Journal of the International Association for the Study of the Liver, 2014

Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.

Datta S et al.

Plos One, 2014

Synergistic effects of A1896, T1653 and T1762/A1764 mutations in genotype c2 hepatitis B virus on development of hepatocellular carcinoma.

Lyu H et al.

Journal of Viral Hepatitis, 2013

[Common mutations of congenital adrenal hyperplasia are also the hotspots for new mutations].

Zhang Q et al.

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, 2012

[Clinical application of DNA sequencing for detecting point mutations in hepatitis B virus associated with drug resistance].

Kong L et al.

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, 2012

Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression.

Kitab B et al.

Plos One, 2012

Comparison study on the complete sequence of hepatitis B virus identifies new mutations in core gene associated with hepatocellular carcinoma.

Zhu Y et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2010

Hepatitis B virus BCP, Precore/core, X gene mutations/genotypes and the risk of hepatocellular carcinoma in India.

Asim M et al.

Journal of Medical Virology, 2010

Clinical significance of genotypes and precore/basal core promoter mutations in HBV related chronic liver disease patients in North India.

Sharma S et al.

Digestive Diseases and Sciences, 2010

Hepatitis B virus core variants modify natural course of viral infection and hepatocellular carcinoma progression.

Sung FY et al.

Gastroenterology, 2009

Hepatitis B virus subgenotypes and basal core promoter mutations in Indonesia.

Utama A et al.

World Journal of Gastroenterology, 2009

Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case-control study.

Fang ZL et al.

The Journal of General Virology, 2008

Application of a novel, rapid, and sensitive oligonucleotide ligation assay for detection of cancer-predicting mutations in the precore and basal core promoter of hepatitis B virus.

Mendy ME et al.

Journal of Clinical Microbiology, 2008

Temporal relationship between hepatitis B virus enhancer II/basal core promoter sequence variation and risk of hepatocellular carcinoma.

Chou YC et al.

Gut, 2008

[Role of mutations on the "hepatitis B virus 'a' determinant hotpoint" to the efficacy of hepatitis B vaccine].

Zhang R et al.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 2007

Genotype and variations in core promoter and pre-core regions are related to progression of disease in HBV-infected patients from Northern Vietnam.

Truong BX et al.

International Journal of Molecular Medicine, 2007

Characteristics of core promoter and precore stop codon mutants of hepatitis B virus in Vietnam.

Huy TT et al.

Journal of Medical Virology, 2004

[Mutations and their significance in the corepromoter region of hepatitis B virus].

Tu H et al.

Zhonghua Yi Xue Za Zhi, 1997

[Detection of p53 gene mutations in hepatocellular carcinoma].

Zhou F et al.

Hua Xi Yi Ke Da Xue Xue Bao = Journal of West China University of Medical Sciences = Huaxi Yike Daxue Xuebao, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."