Varaico: Literature-Extracted Genetic Variants

Gene:AGER
Variant:p.G82S
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AGER

NM_001136.5:p.G82S

Associated Papers

The Taiwan Precision Medicine Initiative provides a cohort for large-scale studies.

Yang HC et al.

Nature, 2025

41092961 (PubMed )
Supplement: 41586_2025_9680_MOESM4_ESM.zip › Supplemental_Data_19.xlsx › Supplemental_Data_19

The association of RAGE gene polymorphisms with inflammatory and oxidative stress markers in diabetic kidney disease patients.

Kamel WA et al.

Molecular Biology Reports, 2025

Rage gene -374T/A polymorphism in South Indian diabetic nephropathy.

Murikipudi RB et al.

Bioinformation, 2025

The Gly82Ser polymorphism in the receptor for advanced glycation endproducts increases the risk for coronary events in the general population.

Grauen Larsen H et al.

Scientific Reports, 2024

Alzheimer's diseases in America, Europe, and Asian regions: a global genetic variation.

Hossain R et al.

Peerj, 2024

38756443 (PubMed )
Supplement: peerj-12-17339-s001.pdf

Evolutionary history of adenomas to colorectal cancer in FAP families.

Yang C et al.

Frontiers in Genetics, 2024

39021676 (PubMed )
Supplement: DataSheet1.ZIP › Somatic › 18R12365.xls › SNVIndel

Decoding the genetic relationship between Alzheimer's disease and type 2 diabetes: potential risk variants and future direction for North Africa.

Boukhalfa W et al.

Frontiers in Aging Neuroscience, 2023

A systematic review and meta-analysis of the relationship between advanced glycation end products ceceptor (RAGE) gene polymorphisms and the risk of inflammatory bowel disease.

Febrinasari RP et al.

Caspian Journal of Internal Medicine, 2023

Exome variants associated with asthma and allergy.

Wjst M

Scientific Reports, 2022

36470944 (PubMed )
Supplement: 41598_2022_24960_MOESM1_ESM.pdf

Polymorphisms in risk genes of type 2 diabetes mellitus could be also markers of susceptibility to periodontitis.

Silva ANA et al.

Archives of Oral Biology, 2022

The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer's Disease.

Busch L et al.

Cells, 2022

The association of AGER and ALDH2 gene polymorphisms with diabetic retinopathy.

Gouliopoulos N et al.

European Journal of Ophthalmology, 2022

Polymorphisms and Gene-Gene Interaction in AGER/IL6 Pathway Might Be Associated with Diabetic Ischemic Heart Disease.

Liu K et al.

Journal of Personalized Medicine, 2022

Single nucleotide variants of receptor for advanced glycation end-products (AGER) gene: is it a new opening in the risk assessment of diabetic retinopathy?-a review.

Ahuja P et al.

Journal, Genetic Engineering & Biotechnology, 2022

Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator.

Yamada M et al.

Communications Biology, 2021

Susceptibility of six polymorphisms in the receptor for advanced glycation end products to type 2 diabetes: a systematic review and meta-analysis.

Cheng H et al.

Endocrine Journal, 2021

Genetics of Diabetic Retinopathy, a Leading Cause of Irreversible Blindness in the Industrialized World.

Bhatwadekar AD et al.

Genes, 2021

Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD.

Pratte KA et al.

Respiratory Research, 2021

Polymorphisms of the receptor for advanced glycation end products as vasculopathy predictor in sickle cell disease.

Safwat NA et al.

Pediatric Research, 2021

Genetic polymorphisms of Cathepsin B are associated with gastric cancer risk and prognosis in a Chinese population.

Ma X et al.

Cancer Biomarkers : Section a of Disease Markers, 2021

Association of rs2070600 in advanced glycosylation end-product specific receptor with prognosis of heart failure.

Li S et al.

Esc Heart Failure, 2020

APOE ε4 Carriers Have a Greater Propensity to Glycation and sRAGE Which Is Further Influenced by RAGE G82S Polymorphism.

Deo P et al.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 2020

Letter to the Editor, Reacting to: "APOE ε4 Carriers Have a Greater Propensity to Glycation and sRAGE Which Is Further Influenced by RAGE G82S Polymorphism".

Mooldijk SS et al.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 2020

The Gly82Ser mutation in AGER contributes to pathogenesis of pulmonary fibrosis in combined pulmonary fibrosis and emphysema (CPFE) in Japanese patients.

Kinjo T et al.

Scientific Reports, 2020

G82S RAGE polymorphism is associated with Alzheimer's disease.

Chellappa RC et al.

Frontiers in Bioscience (elite Edition), 2020

Association of candidate gene polymorphisms with diabetic retinopathy in Chinese patients with type 2 diabetes.

Fan WY et al.

International Journal of Ophthalmology, 2020

G82S RAGE polymorphism influences amyloid-RAGE interactions relevant in Alzheimer's disease pathology.

C RC et al.

Plos One, 2020

Impact of RAGE polymorphisms on urothelial cell carcinoma clinicopathologic characteristics and long-term survival.

Hung SC et al.

Urologic Oncology, 2019

Functional polymorphisms of the receptor for the advanced glycation end product promoter gene in inflammatory bowel disease: a case-control study.

Ciccocioppo R et al.

Clinical and Experimental Medicine, 2019

Association of RAGE gene multiple variants with the risk for COPD and asthma in northern Han Chinese.

Niu H et al.

Aging, 2019

Promoter methylation cooperates with SNPs to modulate RAGE transcription and alter UC risk.

Wang J et al.

Biochemistry and Biophysics Reports, 2019

Association between RAGE variants and the susceptibility to atherosclerotic lesions in Chinese Han population.

Zhang X et al.

Experimental and Therapeutic Medicine, 2019

Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays.

Castaldi PJ et al.

American Journal of Respiratory and Critical Care Medicine, 2019

G82S polymorphism of receptor for advanced glycation end products gene and serum soluble RAGE levels in mild cognitive impairment and dementia of Alzheimer's type patients in Turkish population.

Ataç ZS et al.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 2019

Association of RAGE gene four single nucleotide polymorphisms with the risk, invasion, metastasis and overall survival of gastric cancer in Chinese.

Hu D et al.

Journal of Cancer, 2019

Pathological Implications of Receptor for Advanced Glycation End-Product (AGER) Gene Polymorphism.

Serveaux-Dancer M et al.

Disease Markers, 2019

Determination of SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, and RAGE rs1800625 Single Gene Polymorphisms in Patients with Laryngeal Squamous Cell Carcinoma.

Uloza V et al.

Disease Markers, 2019

Applying Functional Genomics to Chronic Obstructive Pulmonary Disease.

Silverman EK

Annals of the American Thoracic Society, 2018

30759001 (PubMed )
Supplement: annalsats_15_supplement_4_s239.pdf

Genetic susceptibility to cerebrovascular disease: A systematic review.

Griessenauer CJ et al.

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism, 2018

RAGE may act as a tumour suppressor to regulate lung cancer development.

Wu S et al.

Gene, 2018

Decreased soluble RAGE in neutrophilic asthma is correlated with disease severity and RAGE G82S variants.

Lyu Y et al.

Molecular Medicine Reports, 2018

Fasting blood soluble RAGE may be causally implicated in impaired glucose metabolism in Chinese patients with primary hypertension.

Wang Y et al.

Gene, 2018

Polymorphisms in the receptor for advanced glycation end-products (RAGE) gene and circulating RAGE levels as a susceptibility factor for non-alcoholic steatohepatitis (NASH).

Mehta R et al.

Plos One, 2018

Influence of ADAM10 Polymorphisms on Plasma Level of Soluble Receptor for Advanced Glycation End Products and The Association With Alzheimer's Disease Risk.

Huang WH et al.

Frontiers in Genetics, 2018

Genetic association between RAGE polymorphisms and Alzheimer's disease and Lewy body dementias in a Japanese cohort: a case-control study.

Takeshita Y et al.

International Journal of Geriatric Psychiatry, 2017

Genetic predisposition to ischaemic stroke by RAGE and HMGB1 gene variants in Chinese Han population.

Li Y et al.

Oncotarget, 2017

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