Varaico: Literature-Extracted Genetic Variants

Gene:AGO2
Variant:p.D597A
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AGO2

NM_012154.5:p.D597A

Associated Papers

Cutting through the stress: RNA decay pathways at the endoplasmic reticulum.

Ottens F et al.

Trends in Cell Biology, 2024

Essential role of the amino-terminal region of Drosha for the Microprocessor function.

Prabhakar A et al.

Iscience, 2023

Cytoplasmic cleavage of IMPA1 3' UTR is necessary for maintaining axon integrity.

Andreassi C et al.

Cell Reports, 2021

Artificial miRNAs targeting CAG repeat expansion in ORFs cause rapid deadenylation and translation inhibition of mutant transcripts.

Ciesiolka A et al.

Cellular and Molecular Life Sciences : Cmls, 2021

AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2.

Yang A et al.

Nature Communications, 2020

Non-canonical targets destabilize microRNAs in human Argonautes.

Park JH et al.

Nucleic Acids Research, 2017

Slicer-independent mechanism drives small-RNA strand separation during human RISC assembly.

Park JH et al.

Nucleic Acids Research, 2015

Argonaute-bound small RNAs from promoter-proximal RNA polymerase II.

Zamudio JR et al.

Cell, 2014

Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway.

Karamyshev AL et al.

Cell, 2014

Argonaute identity defines the length of mature mammalian microRNAs.

Juvvuna PK et al.

Nucleic Acids Research, 2012

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis.

Cheloufi S et al.

Nature, 2010

Purified Argonaute2 and an siRNA form recombinant human RISC.

Rivas FV et al.

Nature Structural & Molecular Biology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."