Associated Papers
Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk.
Reeve MP et al.
Nature Genetics, 2026
A gene-diet interaction controlling relative intake of dietary carbohydrates and fats.
Nelson NG et al.
Molecular Metabolism, 2022
The central melanocortin system and human obesity.
Yang Y et al.
Journal of Molecular Cell Biology, 2020
Hereditary Haemorrhagic Telangiectasia (HHT) Marked by ACVRL1C1120T Variant Displays Hypopigmented Naevi and Frequent Bleeding Episodes if CYP2C9 Co-Mutated: Clinical Notes & Rationale of Patient Registry.
Minarik L et al.
Folia Biologica, 2020
A Review of Single-Nucleotide Polymorphisms in Orexigenic Neuropeptides Targeting G Protein-Coupled Receptors.
Ericson MD et al.
Acs Chemical Neuroscience, 2018
Analysis of MC4R rs17782313, POMC rs1042571, APOE-Hha1 and AGRP rs3412352 genetic variants with susceptibility to obesity risk in North Indians.
Srivastava A et al.
Annals of Human Biology, 2016
Evaluation of MC4R [rs17782313, rs17700633], AGRP [rs3412352] and POMC [rs1042571] Polymorphisms with Obesity in Northern India.
Srivastava A et al.
Oman Medical Journal, 2014
Complex patterns of genomic admixture within southern Africa.
Petersen DC et al.
Plos Genetics, 2013
The genetics of anorexia nervosa.
Clarke TK et al.
Clinical Pharmacology and Therapeutics, 2012
The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.
Tao YX
Endocrine Reviews, 2010
Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake.
Rask-Andersen M et al.
Brain Research Reviews, 2010
Variants in neuropeptide Y receptor 1 and 5 are associated with nutrient-specific food intake and are under recent selection in Europeans.
Elbers CC et al.
Plos One, 2009
Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI.
Kalnina I et al.
Bmc Medical Genetics, 2009
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009
Analysis of heterogeneity and epistasis in physiological mixed populations by combined structural equation modelling and latent class analysis.
Fenger M et al.
Bmc Genetics, 2008
A rare mutation in AgRP, +79G>A, affects promoter activity.
Sözen MA et al.
European Journal of Clinical Nutrition, 2007
Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset.
Dardennes RM et al.
Psychoneuroendocrinology, 2007
Polymorphisms in the NPY and AGRP genes and body fatness in Dutch adults.
van Rossum CT et al.
International Journal of Obesity (2005), 2006
Agouti-related protein promoter variant associated with leanness and decreased risk for diabetes in West Africans.
Bonilla C et al.
International Journal of Obesity (2005), 2006
Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3.
Creemers JW et al.
Endocrinology, 2006
Two ethnic-specific polymorphisms in the human Agouti-related protein gene are associated with macronutrient intake.
Loos RJ et al.
The American Journal of Clinical Nutrition, 2005
The agouti-related protein and its role in energy homeostasis.
Stütz AM et al.
Peptides, 2005
Gene polymorphisms and their effects in the melanocortin system.
Carroll L et al.
Peptides, 2005
Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness.
de Rijke CE et al.
Biochemical Pharmacology, 2005
Melanocortin-4 receptor gene and physical activity in the Québec Family Study.
Loos RJ et al.
International Journal of Obesity (2005), 2005
Ala67Thr polymorphism in the Agouti-related peptide gene is associated with inherited leanness in humans.
Marks DL et al.
American Journal of Medical Genetics. Part A, 2004
Melanocortin signalling, single nucleotide polymorphism, and eating disorders.
Inui A
International Journal of Psychiatry in Medicine, 2004
Neuropeptide gene polymorphisms and human behavioural disorders.
Inui A
Nature Reviews. Drug Discovery, 2003
The agouti-related protein and body fatness in humans.
Argyropoulos G et al.
International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 2003
A polymorphism in the human agouti-related protein is associated with late-onset obesity.
Argyropoulos G et al.
The Journal of Clinical Endocrinology and Metabolism, 2002
Agouti: from mouse to man, from skin to fat.
Voisey J et al.
Pigment Cell Research, 2002
Drug target discovery by pharmacogenetics: mutations in the melanocortin system and eating disorders.
Adan RA et al.
European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, 2001
The gene structure and minimal promoter of the human agouti related protein.
Brown AM et al.
Gene, 2001
Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha-melanocyte-stimulating hormone genes in severely obese children.
Dubern B et al.
The Journal of Pediatrics, 2001
Association between an agouti-related protein gene polymorphism and anorexia nervosa.
Vink T et al.
Molecular Psychiatry, 2001