Varaico: Literature-Extracted Genetic Variants

Gene:AGTR1
Variant:p.C289W
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AGTR1

NM_000685.5:p.C289W

Associated Papers

Angiotensin II type 1 receptor variants alter endosomal receptor-β-arrestin complex stability and MAPK activation.

Cao Y et al.

The Journal of Biological Chemistry, 2020

Pharmacogenomics of GPCR Drug Targets.

Hauser AS et al.

Cell, 2018

29249361 (PubMed )
Supplement: mmc2.xlsx › MissenseVariants

Combined sequence and sequence-structure-based methods for analyzing RAAS gene SNPs: a computational approach.

Singh KhD et al.

Journal of Receptor and Signal Transduction Research, 2014

A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.

Arsenault J et al.

Pharmacogenetics and Genomics, 2010

Loss-of-function polymorphic variants of the human angiotensin II type 1 receptor.

Hansen JL et al.

Molecular Pharmacology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."