Varaico: Literature-Extracted Genetic Variants

Gene:AHR
Variant:p.R554K
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AHR

NM_001621.5:p.R554K

Associated Papers

Influence of pharmacokinetics-related polymorphisms on asciminib exposure in patients with Japanese chronic myeloid leukemia.

Takahashi N et al.

European Journal of Clinical Pharmacology, 2026

Single Nucleotide Polymorphisms in Oxidative Stress-Related Genes Are Associated with Autism Spectrum Disorders.

Spoto G et al.

International Journal of Molecular Sciences, 2025

Decreased Aryl Hydrocarbon Receptor Gene Expression and Polymorphic Variants Association with Increase COPD Risk.

Sadr M et al.

International Journal of Chronic Obstructive Pulmonary Disease, 2025

Male-biased association of endothelial nitric oxide synthase Asp298Glu substitution (NOS3-c.894G/T) with asthma risk and severity.

Aftabi Y et al.

The Journal of Asthma : Official Journal of the Association for the Care of Asthma, 2023

Aryl Hydrocarbon Receptor Agonism Antagonizes the Hypoxia-driven Inflammation in Cystic Fibrosis.

Pariano M et al.

American Journal of Respiratory Cell and Molecular Biology, 2023

Association of xenobiotic-metabolizing genes polymorphisms with cervical cancer risk in the Tunisian population.

Helaoui A et al.

Molecular Biology Reports, 2023

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Valentine H et al.

Cancer Research Communications, 2022

36643868 (PubMed )
Supplement: crc-22-0245-s07.xlsx › Variants_All_Exonic.exclude_ncR

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM1_ESM.xlsx › sheet_1

Coffee consumption and its interaction with the genetic variant AhR rs2066853 in colorectal cancer risk: a case-control study in Korea.

Lu YT et al.

Carcinogenesis, 2022

Genetic variants affecting chemical mediated skin immunotoxicity.

Rodrigues de Souza I et al.

Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2022

Potential functional variants in AHR signaling pathways are associated with age at puberty in swine.

Nonneman D et al.

Animal Genetics, 2021

The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development.

Kolonko-Adamska M et al.

International Journal of Molecular Sciences, 2021

Deleterious variants in genes regulating mammalian reproduction in Neanderthals, Denisovans and extant humans.

Greer C et al.

Human Reproduction (oxford, England), 2021

33417716 (PubMed )
Supplement: deaa347_supplementary_data.zip › Suppl_Table_SV_Neand_Shared_Extinct_Revised.pdf

Refinement of coding SNPs in the human aryl hydrocarbon receptor gene using ISNPranker: An integrative-SNP ranking web-tool.

Aftabi Y et al.

Computational Biology and Chemistry, 2021

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Umbrella Review on Associations Between Single Nucleotide Polymorphisms and Lung Cancer Risk.

Li X et al.

Frontiers in Molecular Biosciences, 2021

34540891 (PubMed )
Supplement: DataSheet1.zip › Data_Sheet_---Supplementary_Additional_file › Supplementary_Additional_file › Supplementary_Additional_file_S2.docx

Identification of new driver and passenger mutations within APOBEC-induced hotspot mutations in bladder cancer.

Shi MJ et al.

Genome Medicine, 2020

A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing's disease.

De Sousa SMC et al.

Bmc Endocrine Disorders, 2020

Polymorphisms and endometriosis: a systematic review and meta-analyses.

Méar L et al.

Human Reproduction Update, 2020

IGF1 polymorphisms and colon cancer risk in Tunisian population.

Dhifallah H et al.

La Tunisie Medicale, 2020

Somatic Deletion in Exon 10 of Aryl Hydrocarbon Receptor Gene in Human GH-Secreting Pituitary Tumors.

Re A et al.

Frontiers in Endocrinology, 2020

IGF1 polymorphisms and colon cancer risk in Tunisian population.

Dhifallah H et al.

La Tunisie Medicale, 2019

Aryl hydrocarbon receptor rs2066853 gene polymorphisms and male infertility risk: a meta-analysis.

Ren ZJ et al.

Renal Failure, 2019

Evaluation of variation in genes of the arylhydrocarbon receptor pathway for an association with multiple sclerosis.

Zorlu N et al.

Journal of Neuroimmunology, 2019

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China.

Zhang C et al.

Molecular Genetics & Genomic Medicine, 2019

AHR gene-dioxin interactions and birthweight in the Seveso Second Generation Health Study.

Ames J et al.

International Journal of Epidemiology, 2018

Personalizing aromatase inhibitor therapy in patients with breast cancer.

Hamadeh IS et al.

Cancer Treatment Reviews, 2018

A splicing mutation in aryl hydrocarbon receptor associated with retinitis pigmentosa.

Zhou Y et al.

Human Molecular Genetics, 2018

A Functional Aryl Hydrocarbon Receptor Genetic Variant, Alone and in Combination with Parental Exposure, is a Risk Factor for Congenital Heart Disease.

Pulignani S et al.

Cardiovascular Toxicology, 2018

Role of Sequence Variations in AhR Gene Towards Modulating Smoking Induced Lung Cancer Susceptibility in North Indian Population: A Multiple Interaction Analysis.

Budhwar S et al.

Current Genomics, 2018

Lack of association between aryl hydrocarbon receptor gene Arg554Lys polymorphism and male infertility risk: A systematic review and meta-analysis.

Wei Y et al.

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2018

Aryl hydrocarbon receptor gene transitions (c.-742C>T; c.1661G>A) and idiopathic male infertility: a case-control study with in silico and meta-analysis.

Aftabi Y et al.

Environmental Science and Pollution Research International, 2017

Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.

Wang J et al.

Scientific Reports, 2017

28827732 (PubMed )
Supplement: 41598_2017_7737_MOESM1_ESM.pdf

Genetic variants associated with skin aging in the Chinese Han population.

Gao W et al.

Journal of Dermatological Science, 2017

Genetic association of aromatic hydrocarbon receptor and its repressor gene polymorphisms with risk of rheumatoid arthritis in Han Chinese populations.

Cheng L et al.

Medicine, 2017

Aryl hydrocarbon receptor (AhR) rs2066853 gene polymorphism association with infertile oligoasthenoteratozoospermic men and seminal oxidative stress.

Mostafa T et al.

Environmental Science and Pollution Research International, 2017

A comprehensive contribution of genes for aryl hydrocarbon receptor signaling pathway to hypertension susceptibility.

Polonikov AV et al.

Pharmacogenetics and Genomics, 2017

Association of genetic variations with pharmacokinetics and lipid-lowering response to atorvastatin in healthy Korean subjects.

Woo HI et al.

Drug Design, Development and Therapy, 2017

Head-and-neck squamous cell carcinoma risk in smokers: no association detected between phenotype and AHR, CYP1A1, CYP1A2, or CYP1B1 genotype.

Jorge-Nebert LF et al.

Human Genomics, 2016

Role of aryl hydrocarbon receptor polymorphisms on TCDD-mediated CYP1B1 induction and IgM suppression by human B cells.

Kovalova N et al.

Toxicology and Applied Pharmacology, 2016

The association of CYP1A1 genetic polymorphisms and additional gene-gene interaction with ischemic stroke in the eastern Han of China.

Zhang M et al.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2016

Divergent Ah Receptor Ligand Selectivity during Hominin Evolution.

Hubbard TD et al.

Molecular Biology and Evolution, 2016

A Promoter Variant Within the Aryl Hydrocarbon Receptor Gene Is Associated with an Epithelial Barrier Defect in Smokers with Crohn's Disease.

Prager M et al.

Inflammatory Bowel Diseases, 2016

Genetic polymorphisms study of pharmacogenomic VIP variants in Han ethnic of China's Shaanxi province.

Jin T et al.

Environmental Toxicology and Pharmacology, 2016

The c.-190 C>A transversion in promoter region of protamine1 gene as a genetic risk factor for idiopathic oligozoospermia.

Jamali S et al.

Molecular Biology Reports, 2016

The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas.

Lim CH et al.

Oncotarget, 2016

27175599 (PubMed )
Supplement: oncotarget-07-39758-s006.xlsx › TableS5

Genetic polymorphisms of pharmacogenomic VIP variants in the Mongol of Northwestern China.

Jin T et al.

Bmc Genetics, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."