Varaico: Literature-Extracted Genetic Variants

Gene:AICDA
Variant:p.E58Q
Back to variants list

AICDA

NM_020661.4:p.E58Q

Associated Papers

Insights on SNPs of Human Activation-Induced Cytidine Deaminase AID.

Koveshnikova EA et al.

International Journal of Molecular Sciences, 2025

Nonamer dependent RAG cleavage at CpGs can explain mechanism of chromosomal translocations associated to lymphoid cancers.

Paranjape AM et al.

Plos Genetics, 2022

C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency.

Xie X et al.

The Embo Journal, 2022

A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization.

Yewdell WT et al.

Immunity, 2020

TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the Aicda superenhancer.

Lio CJ et al.

Science Immunology, 2019

Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells.

Ma Y et al.

Nature Methods, 2016

PARP activation promotes nuclear AID accumulation in lymphoma cells.

Tepper S et al.

Oncotarget, 2016

Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID.

Le Q et al.

Plos Genetics, 2015

Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching.

Ucher AJ et al.

Journal of Immunology (baltimore, Md. : 1950), 2014

Checkpoint kinase 1 negatively regulates somatic hypermutation.

Frankenberger S et al.

Nucleic Acids Research, 2014

AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].

Ranjit S et al.

Journal of Immunology (baltimore, Md. : 1950), 2011

Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein.

Demorest ZL et al.

The Journal of Biological Chemistry, 2011

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

Ramiro AR et al.

Nature, 2006

Type two hyper-IgM syndrome caused by mutation in activation-induced cytidine deaminase.

Zhu Y et al.

Journal of Medical and Dental Sciences, 2003

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."