Varaico: Literature-Extracted Genetic Variants

Gene:AICDA
Variant:p.G23S
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AICDA

NM_020661.4:p.G23S

Associated Papers

Insights on SNPs of Human Activation-Induced Cytidine Deaminase AID.

Koveshnikova EA et al.

International Journal of Molecular Sciences, 2025

A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification.

Zhou JZ et al.

Biorxiv : the Preprint Server for Biology, 2024

Critical role of WASp in germinal center tolerance through regulation of B cell apoptosis and diversification.

Descatoire M et al.

Cell Reports, 2022

C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion.

Sabouri S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2014

Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense.

Wei M et al.

Nature Immunology, 2011

Separate domains of AID are required for somatic hypermutation and class-switch recombination.

Shinkura R et al.

Nature Immunology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."