Associated Papers
The landscape of germline variants in breast and colorectal cancer susceptibility genes in patients with pituitary tumours.
Orsmond A et al.
Journal of Neuro-oncology, 2025
Genetic evaluation of pediatric pituitary adenomas and USP8-related genotype-phenotype correlations in Cushing's disease.
Zainab R et al.
Pituitary, 2025
Reassessing the role of the p.(Arg304Gln) missense AIP variant in pituitary tumorigenesis.
Loughrey PB et al.
European Journal of Endocrinology, 2025
Germline AIP variants in sporadic young acromegaly and pituitary gigantism: clinical and genetic insights from a Han Chinese cohort.
Xiang B et al.
Endocrine, 2024
Pituitary macroadenomas in childhood and adolescence: a clinical analysis of 7 patients.
Aguilar-Riera C et al.
Clinical Diabetes and Endocrinology, 2023
Novel AIP mutation in exon 6 causing acromegaly in a German family.
Detomas M et al.
Journal of Endocrinological Investigation, 2023
RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas.
Garcia-Rendueles AR et al.
Oncogene, 2021
Clinical and genetic characteristics in patients under 30 years with sporadic pituitary adenomas.
Martínez de LaPiscina I et al.
European Journal of Endocrinology, 2021
miR-34a is upregulated in AIP-mutated somatotropinomas and promotes octreotide resistance.
Bogner EM et al.
International Journal of Cancer, 2020
Risk category system to identify pituitary adenoma patients with AIP mutations.
Caimari F et al.
Journal of Medical Genetics, 2018
Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members' View in an AIP Mutation-Positive Family.
Marques P et al.
International Journal of Endocrinology, 2018
In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism.
Salvatori R et al.
European Journal of Endocrinology, 2017
Germline variants in familial pituitary tumour syndrome genes are common in young patients and families with additional endocrine tumours.
De Sousa SMC et al.
European Journal of Endocrinology, 2017
Rapid Proteasomal Degradation of Mutant Proteins Is the Primary Mechanism Leading to Tumorigenesis in Patients With Missense AIP Mutations.
Hernández-Ramírez LC et al.
The Journal of Clinical Endocrinology and Metabolism, 2016
cAMP-specific PDE4 phosphodiesterases and AIP in the pathogenesis of pituitary tumors.
Bolger GB et al.
Endocrine-related Cancer, 2016
SNPs in the aryl hydrocarbon receptor-interacting protein gene associated with sporadic non-functioning pituitary adenoma.
Hu Y et al.
Experimental and Therapeutic Medicine, 2016
Landscape of Familial Isolated and Young-Onset Pituitary Adenomas: Prospective Diagnosis in AIP Mutation Carriers.
Hernández-Ramírez LC et al.
The Journal of Clinical Endocrinology and Metabolism, 2015
Familial isolated pituitary adenomas (FIPA) and mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene.
Daly AF et al.
Endocrinology and Metabolism Clinics of North America, 2015
Screening for AIP gene mutations in a Han Chinese pituitary adenoma cohort followed by LOH analysis.
Cai F et al.
European Journal of Endocrinology, 2013
Familial isolated pituitary adenoma caused by a Aip gene mutation not described before in a family context.
García-Arnés JA et al.
Endocrine Pathology, 2013
Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene.
Beckers A et al.
Endocrine Reviews, 2013
[Aryl hydrocarbon receptor interacting protein gene and familial isolated pituitary adenomas].
Cai F et al.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, 2012
Familial isolated pituitary adenomas: an emerging clinical entity.
Martucci F et al.
Journal of Endocrinological Investigation, 2012
Familial pituitary adenomas - who should be tested for AIP mutations?
Korbonits M et al.
Clinical Endocrinology, 2012
High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas.
Tichomirowa MA et al.
European Journal of Endocrinology, 2011
Genetic susceptibility in pituitary adenomas: from pathogenesis to clinical implications.
Jaffrain-Rea ML et al.
Expert Review of Endocrinology & Metabolism, 2011
Familial isolated pituitary adenomas: from genetics to therapy.
Guaraldi F et al.
Clinical and Translational Science, 2011
The immunophilin-like protein XAP2 is a negative regulator of estrogen signaling through interaction with estrogen receptor α.
Cai W et al.
Plos One, 2011
The R304X mutation of the aryl hydrocarbon receptor interacting protein gene in familial isolated pituitary adenomas: Mutational hot-spot or founder effect?
Occhi G et al.
Journal of Endocrinological Investigation, 2010
AIP gene and familial isolated pituitary adenomas.
Ozfirat Z et al.
Molecular and Cellular Endocrinology, 2010
Role of the aryl hydrocarbon receptor-interacting protein in familial isolated pituitary adenoma.
Cain JW et al.
Expert Review of Endocrinology & Metabolism, 2010
Aggressive pituitary adenomas occurring in young patients in a large Polynesian kindred with a germline R271W mutation in the AIP gene.
Jennings JE et al.
European Journal of Endocrinology, 2009
The epidemiology and genetics of pituitary adenomas.
Daly AF et al.
Best Practice & Research. Clinical Endocrinology & Metabolism, 2009
[Genetics of familial pituitary adenomas].
Beckers A et al.
Bulletin De L'academie Nationale De Medecine, 2009
The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability.
Vargiolu M et al.
The Journal of Clinical Endocrinology and Metabolism, 2009
Familial pituitary adenomas.
Tichomirowa MA et al.
Journal of Internal Medicine, 2009
Mutations of the gene for the aryl hydrocarbon receptor-interacting protein in pituitary adenomas.
Cazabat L et al.
Hormone Research, 2009
The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.
Leontiou CA et al.
The Journal of Clinical Endocrinology and Metabolism, 2008
Characteristics of familial isolated pituitary adenomas.
Daly AF et al.
Expert Review of Endocrinology & Metabolism, 2007
The clinical, pathological, and genetic features of familial isolated pituitary adenomas.
Beckers A et al.
European Journal of Endocrinology, 2007
AIP gene in pituitary adenoma predisposition.
Vahteristo P et al.
Expert Review of Endocrinology & Metabolism, 2007
Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.
Daly AF et al.
The Journal of Clinical Endocrinology and Metabolism, 2007
Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas.
Barlier A et al.
The Journal of Clinical Endocrinology and Metabolism, 2007
Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update.
Karhu A et al.
Human Molecular Genetics, 2007
Aryl hydrocarbon receptor-interacting protein and acromegaly.
Aaltonen LA
Hormone Research, 2007
[Familial acromegaly. Apropos of a case. Review of the literature].
Tamburrano G et al.
Annales D'endocrinologie, 1992