Associated Papers
High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys.
Berger AH et al.
Frontiers in Immunology, 2025
Association of Autoimmune Regulator Gene Rs2075876 Variant, but Not Gene Expression with Alopecia Areata in Males: A Case-control Study.
Toraih EA et al.
Immunological Investigations, 2020
31601134 (PubMed )
Supplement: supplement_1.pdf
Extended HSR/CARD domain mediates AIRE binding to DNA.
Maslovskaja J et al.
Biochemical and Biophysical Research Communications, 2015
AIRE activated tissue specific genes have histone modifications associated with inactive chromatin.
Org T et al.
Human Molecular Genetics, 2009
The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation.
Chignola F et al.
Nucleic Acids Research, 2009
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression.
Org T et al.
Embo Reports, 2008
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