Varaico: Literature-Extracted Genetic Variants

Gene:AKNA
Variant:p.R1119Q
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AKNA

NM_001317950.2:p.R1119Q

Associated Papers

Pilot clinical trial and phenotypic analysis in chemotherapy-pretreated, metastatic triple-negative breast cancer patients treated with oral TAK-228 and TAK-117 (PIKTOR) to increase DNA damage repair deficiency followed by cisplatin and nab paclitaxel.

Lang JD et al.

Biomarker Research, 2023

37491309 (PubMed )
Supplement: 40364_2023_511_MOESM16_ESM.xlsx › 11JZ

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Witkiewicz AK et al.

Nature Communications, 2015

25855536 (PubMed )
Supplement: ncomms7744-s2.xlsx › MUTATIONS_ALL_CASES

A polymorphism in the AT-hook motif of the transcriptional regulator AKNA is a risk factor for cervical cancer.

Perales G et al.

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 2010

Cervical cancer-associated promoter polymorphism affects akna expression levels.

Martínez-Nava GA et al.

Genes and Immunity, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."