Associated Papers
AKR1C1 and hormone metabolism in lipedema pathogenesis: a computational biology approach.
Kaftalli J et al.
European Review for Medical and Pharmacological Sciences, 2023
Probing the inhibitor selectivity pocket of human 20α-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis.
El-Kabbani O et al.
Bioorganic & Medicinal Chemistry Letters, 2011
Molecular determinants for the stereospecific reduction of 3-ketosteroids and reactivity towards all-trans-retinal of a short-chain dehydrogenase/reductase (DHRS4).
Endo S et al.
Archives of Biochemistry and Biophysics, 2009
Selectivity determinants of inhibitor binding to human 20alpha-hydroxysteroid dehydrogenase: crystal structure of the enzyme in ternary complex with coenzyme and the potent inhibitor 3,5-dichlorosalicylic acid.
Dhagat U et al.
Journal of Medicinal Chemistry, 2008
Human aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms.
Penning TM et al.
Archives of Biochemistry and Biophysics, 2007
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