Varaico: Literature-Extracted Genetic Variants

Gene:AKR1C1
Variant:p.R258C
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AKR1C1

NM_001353.6:p.R258C

Associated Papers

Comprehensive analysis of the deleterious nonsynonymous, non-coding SNPs and cancer variants of human aldo-keto reductase type 1 (AKR1C1) protein and their probable association with disease risk and progression: a computational study.

Nila NN et al.

Biochemistry and Biophysics Reports, 2026

Large-scale whole-exome sequencing analyses identified protein-coding variants associated with immune-mediated diseases in 350,770 adults.

Yang L et al.

Nature Communications, 2024

39009607 (PubMed )
Supplement: 41467_2024_49782_MOESM4_ESM.xlsx › Supplementary_Data_18

In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants.

Takano S et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

Pharmacogenetics of aldo-keto reductase 1C (AKR1C) enzymes.

Alshogran OY

Expert Opinion on Drug Metabolism & Toxicology, 2017

Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.

Arthur JW et al.

Plos One, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."