Varaico: Literature-Extracted Genetic Variants

Gene:AKR1C2
Variant:p.L172Q
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AKR1C2

NM_001393392.1:p.L172Q

Associated Papers

Pharmacogenetics of aldo-keto reductase 1C (AKR1C) enzymes.

Alshogran OY

Expert Opinion on Drug Metabolism & Toxicology, 2017

iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Wang M et al.

Scientific Reports, 2016

27527004 (PubMed )
Supplement: srep31321-s4.xls › SwissvarFilteredMix

Variation in genes encoding the neuroactive steroid synthetic enzymes 5α-reductase type 1 and 3α-reductase type 2 is associated with alcohol dependence.

Milivojevic V et al.

Alcoholism, Clinical and Experimental Research, 2011

Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.

Arthur JW et al.

Plos One, 2010

The effect of allelic variation in aldo-keto reductase 1C2 on the in vitro metabolism of dihydrotestosterone.

Takahashi RH et al.

The Journal of Pharmacology and Experimental Therapeutics, 2009

Human aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms.

Penning TM et al.

Archives of Biochemistry and Biophysics, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."