Varaico: Literature-Extracted Genetic Variants

Gene:AKR1C2
Variant:p.Y55F
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AKR1C2

NM_001393392.1:p.Y55F

Associated Papers

Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases.

Detlefsen AJ et al.

International Journal of Molecular Sciences, 2023

The effect of allelic variation in aldo-keto reductase 1C2 on the in vitro metabolism of dihydrotestosterone.

Takahashi RH et al.

The Journal of Pharmacology and Experimental Therapeutics, 2009

Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.

Heredia VV et al.

Biochemistry, 2004

Structure and function of 3 alpha-hydroxysteroid dehydrogenase.

Penning TM et al.

Steroids, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."