Varaico: Literature-Extracted Genetic Variants

Gene:AKR1C3
Variant:p.R66Q
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AKR1C3

NM_003739.6:p.R66Q

Associated Papers

In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants.

Takano S et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases.

Detlefsen AJ et al.

International Journal of Molecular Sciences, 2023

Lysine acetylation regulates the interaction between proteins and membranes.

Okada AK et al.

Nature Communications, 2021

34753925 (PubMed )
Supplement: 41467_2021_26657_MOESM4_ESM.zip › Bioinformatics.zip › Datasets › Unused › PTMVAR_download.xlsx › Humsavar_overlap_2PSP_PTM5-14-1

Instability of C154Y variant of aldo-keto reductase 1C3.

Endo S et al.

Chemico-biological Interactions, 2017

Pharmacogenetics of aldo-keto reductase 1C (AKR1C) enzymes.

Alshogran OY

Expert Opinion on Drug Metabolism & Toxicology, 2017

NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development.

Baetens D et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017

27490115 (PubMed )
Supplement: gim2016118x1.zip › 20160703_supplemental_data_FINAL_160706.docx

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

Bains OS et al.

The Journal of Pharmacology and Experimental Therapeutics, 2010

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