Varaico: Literature-Extracted Genetic Variants

Gene:AKR1C3
Variant:p.R170C
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AKR1C3

NM_003739.6:p.R170C

Associated Papers

Single-nucleotide polymorphisms in reductase genes are not associated with response to daunorubicin-based remission induction.

Lubieniecka JM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2013

Correlation of aldo-ketoreductase (AKR) 1C3 genetic variant with doxorubicin pharmacodynamics in Asian breast cancer patients.

Voon PJ et al.

British Journal of Clinical Pharmacology, 2013

Pharmacogenetics of genes across the doxorubicin pathway.

Jamieson D et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

Bains OS et al.

The Journal of Pharmacology and Experimental Therapeutics, 2010

Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.

Isokpehi RD et al.

Bioinformatics and Biology Insights, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."