Associated Papers
Base-Excision Repair Mutational Signature in Two Sebaceous Carcinomas of the Eyelid.
Sangiorgi E et al.
Genes, 2023
The lingering effects of Neanderthal introgression on human complex traits.
Wei X et al.
Elife, 2023
Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.
Pape K et al.
Cancers, 2022
The Impact of Age and Genetics on Naltrexone Biotransformation.
Stancil SL et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2022
Molecular genetic analysis of AKR1C2-4 and HSD17B6 genes in subjects 46,XY with hypospadias.
Mares L et al.
Journal of Pediatric Urology, 2020
Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging.
Hou YC et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020
The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.
Punta M et al.
Frontiers in Immunology, 2020
Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione.
Kürschner G et al.
Oncotarget, 2017
Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.
Lonjou C et al.
Bmc Cancer, 2017
Impact of nonsynonymous single nucleotide polymorphisms on in-vitro metabolism of exemestane by hepatic cytosolic reductases.
Platt A et al.
Pharmacogenetics and Genomics, 2016
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.
Yu J et al.
Gut, 2015
Fine mapping analysis confirms and strengthens linkage of four chromosomal regions in familial hypospadias.
Söderhäll C et al.
European Journal of Human Genetics : Ejhg, 2015
Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
Rižner TL et al.
Steroids, 2014
Discovery and refinement of loci associated with lipid levels.
Willer CJ et al.
Nature Genetics, 2013
Polymorphism Thr160Thr in SRD5A1, involved in the progesterone metabolism, modifies postmenopausal breast cancer risk associated with menopausal hormone therapy.
Hein R et al.
Breast Cancer Research and Treatment, 2012
Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.
Bains OS et al.
The Journal of Pharmacology and Experimental Therapeutics, 2010