Associated Papers
Genetic and computational analysis of AKR1C4 gene rs17134592 polymorphism in breast cancer among the Bangladeshi population.
Shaon MA et al.
Scientific Reports, 2025
The lingering effects of Neanderthal introgression on human complex traits.
Wei X et al.
Elife, 2023
Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases.
Detlefsen AJ et al.
International Journal of Molecular Sciences, 2023
Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.
Pape K et al.
Cancers, 2022
The Impact of Age and Genetics on Naltrexone Biotransformation.
Stancil SL et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2022
Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.
Fontana D et al.
Hemasphere, 2020
High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies.
Toulmonde M et al.
Ebiomedicine, 2020
Molecular genetic analysis of AKR1C2-4 and HSD17B6 genes in subjects 46,XY with hypospadias.
Mares L et al.
Journal of Pediatric Urology, 2020
Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging.
Hou YC et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020
Polymorphisms in drug-metabolizing enzymes and steady-state exemestane concentration in postmenopausal patients with breast cancer.
Hertz DL et al.
The Pharmacogenomics Journal, 2017
Pharmacogenetics of aldo-keto reductase 1C (AKR1C) enzymes.
Alshogran OY
Expert Opinion on Drug Metabolism & Toxicology, 2017
Impact of nonsynonymous single nucleotide polymorphisms on in-vitro metabolism of exemestane by hepatic cytosolic reductases.
Platt A et al.
Pharmacogenetics and Genomics, 2016
Whole exome sequencing and single nucleotide polymorphism array analyses to identify germline alterations in genes associated with testosterone metabolism in a patient with androgen insensitivity syndrome and early-onset colorectal cancer.
Disciglio V et al.
Chinese Journal of Cancer, 2016
Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome Sequencing.
Samorodnitsky E et al.
Human Mutation, 2015
A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density.
Rudolph A et al.
Breast Cancer Research : Bcr, 2015
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.
Yu J et al.
Gut, 2015
Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases.
Maciąg A et al.
Bmc Genetics, 2015
Hormone metabolism pathway genes and mammographic density change after quitting estrogen and progestin combined hormone therapy in the California Teachers Study.
Lee E et al.
Breast Cancer Research : Bcr, 2014
Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
Rižner TL et al.
Steroids, 2014
Discovery and refinement of loci associated with lipid levels.
Willer CJ et al.
Nature Genetics, 2013
Single-nucleotide polymorphisms in reductase genes are not associated with response to daunorubicin-based remission induction.
Lubieniecka JM et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2013
Hormone metabolism genes and mammographic density in Singapore Chinese women.
Lee E et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2013
The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort.
Lee E et al.
Breast Cancer Research : Bcr, 2011
Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.
Bains OS et al.
The Journal of Pharmacology and Experimental Therapeutics, 2010
Two allelic variants of aldo-keto reductase 1A1 exhibit reduced in vitro metabolism of daunorubicin.
Bains OS et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2008
Human aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms.
Penning TM et al.
Archives of Biochemistry and Biophysics, 2007
Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study.
Lord SJ et al.
Breast Cancer Research : Bcr, 2005