Varaico: Literature-Extracted Genetic Variants

Gene:AKT1
Variant:p.E319G
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AKT1

NM_001382430.1:p.E319G

Associated Papers

Discovering Deleterious Single Nucleotide Polymorphisms of Human AKT1 Oncogene: An In Silico Study.

Zhang R et al.

Life (basel, Switzerland), 2023

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer.

Thirumal Kumar D et al.

Computers in Biology and Medicine, 2019

Mutational Analysis of Oncogenic AKT1 Gene Associated with Breast Cancer Risk in the High Altitude Ecuadorian Mestizo Population.

López-Cortés A et al.

Biomed Research International, 2018

Prediction of a highly deleterious mutation E17K in AKT-1 gene: An in silico approach.

Khan I et al.

Biochemistry and Biophysics Reports, 2017

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology.

Ibarrola-Villava M et al.

Oncotarget, 2016

26968814 (PubMed )
Supplement: oncotarget-07-22543-s001.pdf

Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

Xu N et al.

Oncotarget, 2016

26646697 (PubMed )
Supplement: oncotarget-07-3884-s001.pdf

Computational identification of significant missense mutations in AKT1 gene.

Shanthi V et al.

Cell Biochemistry and Biophysics, 2014

Hotspot mutations in common oncogenes are infrequent in nasopharyngeal carcinoma.

Jiang N et al.

Oncology Reports, 2014

Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.

Zanaruddin SN et al.

Plos One, 2013

24224046 (PubMed )
Supplement: pone.0080229.s001.zip › File_S1 › Table_S3-OncoCarta_Assays.xlsx › Sheet1

Fresh surgical specimens yield breast stem/progenitor cells and reveal their oncogenic abnormalities.

Pommier SJ et al.

Annals of Surgical Oncology, 2012

21748247 (PubMed )
Supplement: 10434_2011_1892_MOESM2_ESM.pdf
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