Varaico: Literature-Extracted Genetic Variants

Gene:AKT1
Variant:p.Q61L
Back to variants list

AKT1

NM_001382430.1:p.Q61L

Associated Papers

Malignant Melanoma: Landscape of Molecular Markers.

Winter M et al.

Biomedicines, 2026

Oral Melanocytic Neoplasms: A Narrative Review.

Maldonado-Mendoza J

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2025

Discovering Deleterious Single Nucleotide Polymorphisms of Human AKT1 Oncogene: An In Silico Study.

Zhang R et al.

Life (basel, Switzerland), 2023

37511907 (PubMed )
Supplement: life-13-01532-s001.zip › Supplementary_Table_S2.pdf

Recurrent PTPN14 Mutations in Trichilemmoma: Evidence for Distinct Pathways of Molecular Pathogenesis.

Russell-Goldman E et al.

The American Journal of Dermatopathology, 2022

Clinicopathological and molecular characteristics of patients with hypermutant lung cancer: A retrospective cohort study.

Zhang H et al.

Oncology Letters, 2021

33692861 (PubMed )
Supplement: Supplementary_Data.pdf

RAS as a positive predictive biomarker: focus on lung and colorectal cancer patients.

Malapelle U et al.

European Journal of Cancer (oxford, England : 1990), 2021

Long-read sequencing for non-small-cell lung cancer genomes.

Sakamoto Y et al.

Genome Research, 2020

32887687 (PubMed )
Supplement: supp_gr.261941.120_Supplemental_material.docx

Detection of RAS and RAS-associated alterations in primary lung adenocarcinomas. A correlation between molecular findings and tumor characteristics.

Shaukat I et al.

Human Pathology, 2019

Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer.

Osumi H et al.

Cancer Medicine, 2019

Mutation analysis of the EGFR pathway genes, EGFR, RAS, PIK3CA, BRAF, and AKT1, in salivary gland adenoid cystic carcinoma.

Saida K et al.

Oncotarget, 2018

29682203 (PubMed )
Supplement: oncotarget-09-17043-s001.pdf

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas.

Shimura T et al.

Oncotarget, 2018

29416736 (PubMed )
Supplement: oncotarget-09-1852-s001.pdf

Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients.

Chen Q et al.

Oncotargets and Therapy, 2018

Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Illei PB et al.

Oncotarget, 2017

29228562 (PubMed )
Supplement: oncotarget-08-96684-s001.pdf

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.

Gong J et al.

Oncotarget, 2017

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients.

Hsu HC et al.

Oncotarget, 2016

26989027 (PubMed )
Supplement: oncotarget-07-22257-s001.pdf

Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.

Griewank KG et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

Evidence of a low prevalence of RAS mutations in a large medullary thyroid cancer series.

Ciampi R et al.

Thyroid : Official Journal of the American Thyroid Association, 2013

High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.

Ney JT et al.

Archives of Pathology & Laboratory Medicine, 2012

Keratinocytic epidermal nevi are associated with mosaic RAS mutations.

Hafner C et al.

Journal of Medical Genetics, 2012

Interleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitment.

de Keijzer S et al.

Plos One, 2011

Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma.

Santarpia L et al.

Cancer, 2010

Spatiotemporal regulation of Ras activity provides directional sensing.

Zhang S et al.

Current Biology : Cb, 2008

The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway during Dictyostelium development.

Aubry L et al.

Developmental Biology, 2003

A comprehensive procedural approach to genotyping KRAS and BRAF from paraffin embedded tissues for diagnostic purposes.

Palmirotta R et al.

In Vivo (athens, Greece), 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."