Varaico: Literature-Extracted Genetic Variants

Gene:AKT1
Variant:p.Q61R
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AKT1

NM_001382430.1:p.Q61R

Associated Papers

Oral Melanocytic Neoplasms: A Narrative Review.

Maldonado-Mendoza J

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2025

Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.

Deycmar S et al.

Journal of Translational Medicine, 2024

The Clinicopathological Correlation of KRAS Mutation and PTEN Expression Status in Primary and Metastatic Colorectal Carcinoma.

Hassan RT et al.

Cureus, 2024

Genomic profiling informs diagnoses and treatment in vascular anomalies.

Li D et al.

Nature Medicine, 2023

Sclerosing Polycystic Adenoma of Salivary Glands: A Novel Neoplasm Characterized by PI3K-AKT Pathway Alterations-New Insights Into a Challenging Entity.

Skálová A et al.

The American Journal of Surgical Pathology, 2022

Blockade of mutant RAS oncogenic signaling with a special emphasis on KRAS.

Roskoski R

Pharmacological Research, 2021

Proteogenomic characterization of pancreatic ductal adenocarcinoma.

Cao L et al.

Cell, 2021

RAS as a positive predictive biomarker: focus on lung and colorectal cancer patients.

Malapelle U et al.

European Journal of Cancer (oxford, England : 1990), 2021

Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer.

Osumi H et al.

Cancer Medicine, 2019

Metastases risk in thin cutaneous melanoma: prognostic value of clinical-pathologic characteristics and mutation profile.

Richetta AG et al.

Oncotarget, 2018

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas.

Shimura T et al.

Oncotarget, 2018

29416736 (PubMed )
Supplement: oncotarget-09-1852-s001.pdf

Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients.

Chen Q et al.

Oncotargets and Therapy, 2018

Impact of next-generation sequencing on the clinical diagnosis of pancreatic cysts.

Jones M et al.

Gastrointestinal Endoscopy, 2016

Mosaic Neurocutaneous Disorders and Their Causes.

Ruggieri M et al.

Seminars in Pediatric Neurology, 2015

RAS proto-oncogene in medullary thyroid carcinoma.

Moura MM et al.

Endocrine-related Cancer, 2015

Concomitant RAS, RET/PTC, or BRAF mutations in advanced stage of papillary thyroid carcinoma.

Zou M et al.

Thyroid : Official Journal of the American Thyroid Association, 2014

Novel somatic and germline mutations in intracranial germ cell tumours.

Wang L et al.

Nature, 2014

Reporting tumor molecular heterogeneity in histopathological diagnosis.

Mafficini A et al.

Plos One, 2014

Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.

Griewank KG et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

Evidence of a low prevalence of RAS mutations in a large medullary thyroid cancer series.

Ciampi R et al.

Thyroid : Official Journal of the American Thyroid Association, 2013

Keratinocytic epidermal nevi are associated with mosaic RAS mutations.

Hafner C et al.

Journal of Medical Genetics, 2012

KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.

Tie J et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

21239505 (PubMed )
Supplement: 10780432ccr101720-sup-supplementary_tables_s1-s4.pdf

Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma.

Santarpia L et al.

Cancer, 2010

A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.

Fumagalli D et al.

Bmc Cancer, 2010

Lack of cytoplasmic ERK activation is an independent adverse prognostic factor in primary cutaneous melanoma.

Jovanovic B et al.

The Journal of Investigative Dermatology, 2008

A comprehensive procedural approach to genotyping KRAS and BRAF from paraffin embedded tissues for diagnostic purposes.

Palmirotta R et al.

In Vivo (athens, Greece), 0

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